Advertisement

Uterine Body

  • Donna M. Coffey
  • Ibrahim Ramzy
Chapter
Part of the Frozen Section Library book series (FROZEN, volume 11)

Abstract

Intraoperative consultations of material from the uterine body are mostly related to evaluation of specimens from hysterectomies, performed for a wide variety of reasons. These reasons will be considered first, followed by a discussion of the different specimens submitted from the operating room and the related clinical background. The last part of the chapter considers selected conditions and differential diagnostic issues associated with these entities.

Keywords

Endometrial Carcinoma Myometrial Invasion Endometrial Polyp Uterine Sarcoma Smooth Muscle Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Recommended Reading

  1. Abeler VM, Nenodovic M. Diagnostic immunohistochemistry in uterine sarcomas: A study of 397 cases. Internat J Gynecol Pathol. 2011;30:336–43.PubMedGoogle Scholar
  2. Altintas A, Cosar E, Vardar MA, et al. Intraoperative assessment of depth of myometrial invasion in endometrial carcinoma. Eur J Gynaecol Oncol. 1999;20:329–31.PubMedGoogle Scholar
  3. Atad J, Weill S, Ben-David Y, et al. Intraoperative frozen section examination of myometrial invasion depth in patients with endometrial carcinoma. Int J Gynecol Cancer. 1994;4:352–5.PubMedCrossRefGoogle Scholar
  4. Attard MS, Coutts M, Devaja O, et al. Accuracy of frozen section diagnosis at surgery in pre-malignant and malignant lesions of the endometrium. Eur J Gynaecol Oncol. 2008;29:435–40.Google Scholar
  5. Barakat RR, Bevers MW, Gershenson DM, Hoskins WH, editors. MD Anderson Cancer Center and Memorial Sloan-Kettering Cancer Center Handbook of gynecologic oncology. 2nd ed. London: Martin Dunitz; 2002.Google Scholar
  6. Berek JS, Hacker NF, editors. Berek & Hacker’s practical gynecologic oncology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2009.Google Scholar
  7. Bjornsson BL, Nelson BE, Reale FR, Rose PG. Accuracy of frozen section for lymph node metastasis in patients undergoing radical hysterectomy for carcinoma of the cervix. Gynecol Oncol. 1993;51:50–3.PubMedCrossRefGoogle Scholar
  8. Boronow RC, Morrow CP, Creasman WT, et al. Surgical staging in endometrial cancer: clinical-pathologic findings of a prospective study. Obstet Gynecol. 1984;63:825–32.PubMedGoogle Scholar
  9. Creasman WT, Morrow CP, Bundy BN, et al. Surgical pathologic spread of endometrial cancer, a gynecologic oncology group study. Cancer. 1987;60:2035–41.PubMedCrossRefGoogle Scholar
  10. Crum CP, Lee KR, editors. Diagnostic gynecologic and obstetric pathology. Philadelphia, PA: Elsevier Saunders; 2006.Google Scholar
  11. Daniel AG, Peters 3rd WA. Accuracy of office and operating room curettage in the grading of endometrial carcinoma. Obstet Gynecol. 1988;71:612–4.PubMedGoogle Scholar
  12. DiSaia PJ, Creasman WT. Clinical gynecologic oncology. 7th ed. Philadelphia, PA: Mosby-Elsevier; 2007.Google Scholar
  13. Fanfani F, Ludovisi M, Zannoni GF, et al. Frozen section examination of pelvic lymph nodes in endometrial and cervical cancer: accuracy in patients submitted to neoadjuvant treatments. Gynecol Oncol. 2004;94:779–84.PubMedCrossRefGoogle Scholar
  14. Fishman A et al. The value of transvaginal sonography in the preoperative assessment of myometrial invasion in high and low grade endometrial cancer and in comparison to frozen section in grade 1 disease. Eur J Gynaecol Oncol. 2000;21:128–30.PubMedGoogle Scholar
  15. Forde GK, Carlson JW, Downey GO, et al. A quality process study of lymph node evaluation in endometrial cancer. Internat J Gynecol Pathol. 2011;30:335–9.PubMedCrossRefGoogle Scholar
  16. Goff BA, Rice LW. Assessment of depth of myometrial invasion in endometrial adenocarcinoma. Gynecol Oncol. 1990;38:46–8.PubMedCrossRefGoogle Scholar
  17. Hasenburg A et al. Evaluation of lymph nodes in squamous cell carcinoma of the cervix: touch imprint cytology versus frozen section histology. Int J Gynecol Cancer. 1999;9:337–41.PubMedCrossRefGoogle Scholar
  18. Hoskins W, Perez CA, Young RC. Principles and practice of gynecologic oncology. 3rd ed. Philadelphia, PA: Lippincott William & Wilkins; 2000.Google Scholar
  19. Indermaur M, Shoup B, Tebes S, et al. The accuracy of frozen pathology at time of hysterectomy in patients with complex atypical hyperplasia on preoperative biopsy. Residents’ papers. Am J Obstet Gynecol. 2007;196:e40–2.PubMedCrossRefGoogle Scholar
  20. Kir G, Kir M, Cetiner H, et al. Diagnostic problems on frozen section ­examination of myometrial invasion in patients with endometrial ­carcinoma with special emphasis on the pitfalls of deep adenomyosis with carcinomatous involvement. Eur J Gynaecol Oncol. 2004;25:211–4.PubMedGoogle Scholar
  21. Korczynski J, Jesionek-Kupnicka D, Gottwald L, et al. Comparison of FIGO 1989 and 2009 recommendations on staging of endometrial carcinoma. Pathologic analysis and cervical status in 123 consecutive cases. Internat J Gynecol Pathol. 2011;30:328–34.PubMedCrossRefGoogle Scholar
  22. Kucera E, Kainz RC, Sliutz G, et al. Accuracy of intraoperative frozen section diagnosis in stage I endometrial adenocarcinoma. Gynecol Obstet Invest. 2000;49:62–6.PubMedCrossRefGoogle Scholar
  23. Lopez-Garcia MA, Palacios J. Pathologic and molecular features of uterine carcinosarcomas. Semin Diagn Pathol 2010;27:274–86.Google Scholar
  24. Mills SE. Decidua and squamous metaplasia in abdominopelvic lymph nodes. Int J Gynecol Pathol. 1983;2:209–15.PubMedCrossRefGoogle Scholar
  25. Noriaki S, Chikara S, Naoki T, et al. Incidence and distribution pattern of pelvic and paraaortic lymph node metastasis in patients with Stage IB, IIA and IIB cervical carcinoma treated with radical hysterectomy. Cancer. 1999;85:1547–54.CrossRefGoogle Scholar
  26. Noumoff JS, Menzin A, Mikuta J, et al. The ability to evaluate prognostic variables on frozen section in hysterectomies performed for endometrial carcinoma. Gynecol Oncol. 1991;42:202–8.PubMedCrossRefGoogle Scholar
  27. Nucci MR, Oliva E. Gynecologic pathology. London: Elsevier Churchill Livingstone; 2009 (Volume in the series foundations in diagnostic pathology).Google Scholar
  28. Robboy SJ, Anderson MC, Russell P. Pathology of the female reproductive tract. London: Churchill Livingstone; 2002.Google Scholar
  29. Shim JU, Rose PG, Reale FR, et al. Accuracy of frozen section diagnosis at surgery in clinical stage I and II endometrial carcinoma. Am J Obstet Gynecol. 1992;166:1335–8.PubMedGoogle Scholar
  30. Takeshima N, Hirai Y, Hasumi K. Prognostic validity of neoplastic cells with notable nuclear atypia in endometrial cancer. Obstet Gynecol. 1998;92:119–23.PubMedCrossRefGoogle Scholar
  31. Wu DC, Hirschowitz S, Nararajan S. Ectopic decidua of pelvic lymph nodes. Arch Pathol Lab Med. 2005;129:117–20.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of Pathology and Genomic Medicine The Methodist HospitalWeill Medical College of Cornell UniversityHoustonUSA
  2. 2.University of CaliforniaIrvineUSA

Personalised recommendations