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Actin Doesn’t Do the Locomotion: Secretion Drives Cell Polarization

  • Chapter
Trafficking Inside Cells

Part of the book series: Molecular Biology Intelligence Unit ((MBIU))

Abstract

Cell polarity refers to the asymmetry in cell shape resulting from asymmetrical protein distribution within a cell in order to serve a specialized cell function or directional cell division. Mechanisms of cell polarization are conserved through evolution and are achieved by conserved multiprotein complexes. Recent advances have revealed that protein transport plays a key role in both the mechanisms and the regulation of cell polarity.

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Authors and Affiliations

  1. Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, 14853-6401, USA

    Richard A. Cerione

  2. Institute for Biotechnology and Life Sciences, Cornell University, Ithaca, New York, USA

    Mahasin Osman

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Correspondence to Richard A. Cerione .

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Osman, M., Cerione, R.A. (2009). Actin Doesn’t Do the Locomotion: Secretion Drives Cell Polarization. In: Trafficking Inside Cells. Molecular Biology Intelligence Unit. Springer, New York, NY. https://doi.org/10.1007/978-0-387-93877-6_18

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