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Fluorophores for Optical Imaging

  • Iain Johnson
Chapter

Abstract

Optical imaging using fluorescent probes, along with related biomedical imaging technologies such as PET, SPECT, MRI and bioluminescence, represents a return to in situ observational methods of biological discovery in contrast to the reductionist molecular level genomic and proteomic methods that have dominated biomedical research for the past 50 years. This chapter will delineate and compare the properties of fluorescent probes, which are the molecular constructs responsible for contrast generation in most fluorescence imaging applications. For this reason, fluorescence microscopy and other imaging technologies that can deliver this essential contextual information are of ever-increasing importance in biomedical research. This chapter will delineate and compare the properties of fluorescent probes, which are the molecular constructs responsible for contrast generation in most fluorescence imaging applications.

Keywords

Fluorescent Probe Fluorescence Quantum Yield Multiplex Detection Contrast Generation Surface Coating Layer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Life Technologies CorporationEugeneUSA

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