Optical Imaging of Cancer: Neuro-oncologic Applications
Tumors of the central nervous system (CNS) present unique challenges to the clinician with respect to diagnosis and therapeutics. Location of the tumors within the brain confined by the calvaria and the complex boney architecture of the skull base also present difficulty in efficiently imaging lesions especially in computer tomographic (CT) imaging of lesions in the posterior fossa. The most common central nervous system (CNS) tumors are metastatic lesions that arise from tumors elsewhere in the body, of which lung and breast primaries constitute a large proportion. Primary brain tumors, those that arise from cellular constituents residing within the brain such as glial cells and neurons, are particularly vexing in both diagnosis and treatment improvements in imaging technology with the combined use of neurophysiological monitoring have lead to more aggressive surgical resections of tumors.
KeywordsGlioma Cell Neural Stem Cell Primary Brain Tumor Molecular Beacon Computer Tomographic
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