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Optical Imaging of Cancer: Enhancing Detection and Resection

  • Kent T. Keyser
  • Christianne E. Strang
Chapter

Abstract

The purpose of this chapter is to provide a brief review of selected principles of microscopy and an overview of contemporary imaging methods, with an emphasis on fluorescence techniques used in biomedical research in general and cancer research in particular. For additional information, the reader is referred to the end of the chapter for a short list of excellent references and web sites that provide useful information.

Keywords

Focal Plane Fluorescence Resonance Energy Transfer Fluorescence Lifetime Numerical Aperture Excitation Light 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References and Recommended Readings

  1. Becker, W. and Bergman, A. (2003) Lifetime imaging for optical microscopy, http://www.becker-hickl.de/abstracts/Lifetime%20Imaging%20Techniques%20for%20Optical%20Microscopy.htm
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Review Articles

  1. Michalet, X., Kapanidis, A.N., Laurence, T., Pinaud, F., Doose, S., Pflughoefft, M., Weiss, S. (2003) The power and prospects of fluorescence microscopies and spectroscopies. Annual Review of Biophysics and Biomolecular Structure 32:161–182, doi:10.1146/annurev. biophys.32.110601.142525.CrossRefPubMedGoogle Scholar
  2. Wang, J., Shyy, J. Y-J., Chien S. (2008) Fluorescence proteins, live-cell imaging, and mechanobiology: seeing is believing. Annual Review of Biomedical Engineering 10, doi:10.1146/annurev. bioeng.010308.161731.Google Scholar
  3. So, P.T. C., Dong, C.Y., Masters, B.R., Berland, K.M. (2000) Two-photon excitation fluorescence microscopy. Annual Review of Biomedical Engineering 2:399–429, doi:10.1146/annurev. bioeng.2.1.399.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Vision SciencesUniversity of Alabama at BirminghamBirminghamUSA

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