Vector-Borne Transmission: Malaria, Dengue, and Yellow Fever

Part of the Statistics for Biology and Health book series (SBH)


At least 2 billion people live in malarious areas (Snow et al. 2005). The disease primarily affects poor populations in tropical and subtropical areas, where the temperature and rainfall are most suitable for the development of the alariacausing Plasmodium parasites in Anopheles mosquitoes. This limited geographic distribution is no necessity: malaria once occurred widely in temperate areas, including Western Europe and the USA. The infection receded with economic development and public health measures. It was finally eliminated in the USA between 1947 and 1951 through a campaign that included household spraying of the insecticide dichloro-diphenyl-trichloroethane (DDT).


Severe Malaria Indoor Residual Spray Dengue Virus Dengue Fever Yellow Fever 
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  1. Barros MLB, Boecken G (1996) Jungle yellow fever in the central Amazon. Lancet 348:969–970CrossRefGoogle Scholar
  2. Berkley J, Mwarumba S, Bramham K, Lowe B, Marsh K (1999) Bacteraemia complicating severe malaria in children. Trans R Soc Trop Med Hyg 93:283–286CrossRefGoogle Scholar
  3. Ceesay SJ, Casals-Pascual C, Erskine J, Anya SE, Duah NO, Fulford AJ, Sesay SS, Abubakar I, Dunyo S, Sey O, Palmer A, Fofana M, Corrah T, Bojang KA, Whittle HC, Greenwood BM, Conway DJ (2008) Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis. Lancet 372:1545–1554CrossRefGoogle Scholar
  4. Garret-Jones C (1964) Prognosis for interruption of malaria transmission through assessment of the mosquito’s vectorial capacity. Nature 204:1173–1175CrossRefGoogle Scholar
  5. Gibbons RV, Vaughn DW (2002) Dengue: an escalating problem. BMJ 324: 1563–1566CrossRefGoogle Scholar
  6. Greenwood BM, Fidock DA, Kyle DE, Kappe SH, Alonso PL, Collins FH, Duffy PE (2008) Malaria: progress, perils, and prospects for eradication.J Clin Invest 118(4):1266–1276CrossRefGoogle Scholar
  7. Gubler DJ (1997) Epidemic dengue/dengue hemorrhagic fever: A global public health problem in the 21st century. In: World Health Organization, the South-East Asia and Western Pacific Region. Dengue Bulletin – Vol. 21. New Delhi: WHO; pp. 1–13Google Scholar
  8. Halstead SB (1989) Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Rev Infect Dis 11: S830–S839CrossRefGoogle Scholar
  9. Halstead SB (2002) Dengue Curr Opin Infect Dis 15: 471–476CrossRefGoogle Scholar
  10. Jelinek T, Mühlberger N, Harms G et al (2002) Epidemiology and clinical features of imported dengue fever in Europe: Sentinel surveillance data from TropNetEurop. Clin Infect Dis 35: 1047–1052CrossRefGoogle Scholar
  11. Kliks SC, Nimmanitya S, Nisalak A, Burke DS (1988) Evidence that maternal dengue antibodies are important in the development of dengue hemorrhagic fever in infants. Am J Trop Med Hyg 38: 411–419Google Scholar
  12. Korenromp EL et al. (2005) Malaria attributable to the HIV-1 epidemic, sub-Saharan Africa. Emerg Infect Dis 11:1410–1419Google Scholar
  13. Kwiatkowski DP (2005) How malaria has affected the human genome and what human genetics can teach us about malaria. Am J Hum Genet 77:171–192CrossRefGoogle Scholar
  14. Lifson A (1996) Mosquitos, models, and dengue. Lancet 347: 1201–1202CrossRefGoogle Scholar
  15. McBride WJ, Bielefeldt-Ohmann H (2000) Dengue viral infections; pathogenesis and epidemiology. Microbes infect 2000; 2: 1041–1050CrossRefGoogle Scholar
  16. Monath TP (2001) Yellow fever: an update. The Lancet Infect Dis 1:11–20CrossRefGoogle Scholar
  17. Moody A (2002) Rapid diagnostic tests for malaria parasites. Clin Microbiol Rev 15:66–78CrossRefGoogle Scholar
  18. Pinheiro F, Nelson M (1997) Re-emergence of dengue and emergence of dengue haemorrhagic fever in the Americas. In: World Health Organization, the South-East Asia and Western Pacific Region. Dengue Bulletin – Vol. 21. New Delhi: WHO; pp. 16–23Google Scholar
  19. Promed post (2008) Malaria, Europa and US, from Gambia. /pls/otn/f?p=2400:1001:2917102731875827::NO::F2400_P1001_BACK_PAGE,F2400_ P1001_PUB_MAIL_ID:1000,74978
  20. Reyburn H et al. (2005) Association of transmission intensity and age with clinical manifestations and case fatality of severe Plasmodium falciparum malaria. JAMA 293:1461–1470CrossRefGoogle Scholar
  21. Rigau-Perez J, Clark G, Gubler D et al. (1998) Dengue and dengue haemorrhagic fever. Lancet 352: 971–977CrossRefGoogle Scholar
  22. Romi R (2001) Aedes albopictus in Italy: an underestimated health problem. Ann Inst Super Sanita 37: 241–247Google Scholar
  23. Rowe AK et al. (2006) The burden of malaria mortality among African children in the year 2000. Int J Epidemiol 35:691–704CrossRefGoogle Scholar
  24. Snow RW, Guerra CA, Noor AM, Myint HY, Hay SI (2005) The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434:214–217CrossRefGoogle Scholar
  25. Tanner M, de Savigny D (2008) Malaria eradication back on the table. Bull. World Health Organ 86, 82CrossRefGoogle Scholar
  26. Thein S, Aung MM, Shwe TN et al (1997) Risk factors in dengue shock syndrome. Am J Trop Med Hyg 56: 566–572Google Scholar
  27. White NJ (1999) Variation in virulence of dengue virus. Lancet 23: 1401–1402CrossRefGoogle Scholar
  28. WHO (1999) Making a difference. The World Health Report. Health Millions 25:3–5Google Scholar
  29. WHO (2000) Report on Global Surveillance of Epidemic-prone Infectious Diseases, World Health Organization 2000, WHO/CDS/CSR/ISR/2000.1;; last accessed 30 June 2008
  30. WHO (2005) International Health Regulations. Geneva: World Health Organization, 1–60.
  31. WHO (2008a) Epidemic and Pandemic Alert and Response. Yellow Fever in Burkina Faso.
  32. WHO (2008b) DengueNet; accessed 30 June 2008
  33. WHO (2008c) Epidemic and Pandemic Alert and Response. Yellow Fever in Paraguay.

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Berlin Center for Travel and Tropical MedicineBerlinGermany

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