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Principles and Concepts of Behavioral Medicine pp 713–735Cite as

Using Genomic Knowledge to Improve Health Promotion Interventions in the Developing World

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Abstract

There has been considerable optimism about the potential to use new genomic knowledge to address public health challenges in the developing world. In this chapter, we describe how emerging genomic knowledge could lead to improvements in interventions to promote health behaviors in the over 100 countries with low or middle income per capita (LMICs). We suggest two possible, and as yet untested, opportunities for applying genomics-informed health promotion efforts in LMICs: (a) to inform risk stratification and allocation of limited health promotion resources and (b) to develop targeted risk communications and motivate adherence to behavioral recommendations. We consider these opportunities against the backdrop of social challenges presented by LMIC contexts. To do so, we draw from the experiences of an ongoing program of research among genetically high-risk families in rural Ethiopia. We conclude with recommendations for future formative and comparative effectiveness research to bring evidence to ongoing debates about the potential for genomic contributions to promote health globally.

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Acknowledgments

The authors would like to acknowledge the contributions of Ms. Emily Schiller and Ms. Leah Abrams in assisting with the preparation of this chapter.

Author information

Authors and Affiliations

  1. Behavioral Sciences and Health Education Department, Rollins School of Public Health, Emory University, Atlanta, GA, USA

    Colleen M. McBride

  2. Department of Physical Therapy and Athletic Training, Northern Arizona University, Flagstaff, AZ, USA

    Hendrik D. de Heer

  3. Division of Intramural Population Health Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA

    Fasil Tekola Ayele

  4. Brighton and Sussex Medical School, University of Sussex, Falmer Campus, Brighton, UK

    Gail Davey

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  1. Colleen M. McBride
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  2. Hendrik D. de Heer
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  3. Fasil Tekola Ayele
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  4. Gail Davey
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Corresponding author

Correspondence to Colleen M. McBride .

Editor information

Editors and Affiliations

  1. Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    Edwin B. Fisher

  2. Psychological Sciences, University of California, Merced, Merced, CA, USA

    Linda D. Cameron

  3. Department of Psychological and Brain Sciences and Department of Internal Medicine, The University of Iowa, Iowa City, IA, USA

    Alan J. Christensen

  4. Department of Clinical Psychology and Psychotherapy, University of Zurich, Zürich, Switzerland

    Ulrike Ehlert

  5. School of Public Health, Peking University Health Science Center, Beijing, China

    Yan Guo

  6. Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia

    Brian Oldenburg

  7. Departments of Medical Psychology, Academic Medical Center (AMC) and VU University Medical Center (VUMC), Amsterdam, The Netherlands

    Frank J. Snoek

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McBride, C.M., de Heer, H.D., Ayele, F.T., Davey, G. (2018). Using Genomic Knowledge to Improve Health Promotion Interventions in the Developing World. In: Fisher, E., et al. Principles and Concepts of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-93826-4_24

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