Approximately 8,500 cases/year in the US with male predominance (3:1). Etiologies include consumption of alcohol, tobacco, betal and areca nuts, and HPV infection. Recent decrease in the incidence of tobacco-related cancers. Recent increase in HPV-related incidence rates attributed to changing sexual practices. HPV-related cancers appear to occur at a slightly younger age and have better survival rates when treated with radiotherapy and chemotherapy as compared to non-HPV-related cancers. Second primary tumors in the upper aerodigestive tract and lung occur in ∼25% of patients due to risk factors and lifestyle.
KeywordsRegional Lymph Node Metastasis Great Dimension Lateral Pterygoid Muscle Contralateral Lymph Node Preventive Dental Care
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