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Non-small Cell Lung Cancer

  • Siavash Jabbari
  • Eric K. Hansen
  • Daphne A. Haas-Kogan
Chapter

Abstract

Most common noncutaneous cancer in the world. Second most common cancer in the US, behind prostate in men and breast in women. No. 1 cause of cancer death in the US and worldwide. >90% of cases are associated with smoking or involuntary smoking. Second most common cause in the US is radon. Asbestos exposure is associated with 3–4% of cases. Risk of tobacco-induced second primary is ∼2–3% per year. The surgical lymph node levels 1–9 correspond to N2 nodes, and levels 10–14 correspond to N1 nodes. 1 = high mediastinal, 2 = upper paratracheal, 3 = pre and retrotracheal, 4 = lower paratracheal, 5 = AP window, 6 = paraaortic, 7 = subcarinal, 8 = paraesophageal below carina, 9 = pulmonary ligament, 10 = hilar, 11 = interlobar, 12 = lobar, 13 = segmental, and 14 = subsegmental. Adenocarcinoma comprises 40–50% of cases. It tends to be peripherally located; it has a high propensity to metastasize (frequently to the brain).

Keywords

Main Bronchus Visceral Pleura Brachial Plexus Palsy Superior Sulcus Superior Sulcus Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York 2010

Authors and Affiliations

  • Siavash Jabbari
    • 1
  • Eric K. Hansen
    • 2
  • Daphne A. Haas-Kogan
    • 1
  1. 1.Radiation OncologyUniversity of California San FranciscoSan FranciscoUSA
  2. 2.Radiation Oncology, The Oregon ClinicProvidence St. Vincent Medical CenterPortlandUS

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