Management Approaches to Dealing with Pharmaceuticals and Hormones from CAFOs

  • Laurence Shore
  • Amy Pruden
Part of the Emerging Topics in Ecotoxicology book series (ETEP, volume 1)


Hormones and most pharmaceuticals can be prevented from entering the environment by simple technologies. Composting is extremely effective in destroying all compounds tested to date. Similarly, silaging is effective in removing most compounds. Closing off the CAFO from the environment leaves the question of what to do with the huge amount of manure accumulated. Fortunately, the demand for organic fertilizers has risen in the last decade as the result of increased interest in organic farming and the rise in the cost of inorganic fertilizers. In addition, to composting, the material can be converted to biogas. Controlling run-off and other common sense best management practices are also likely to help prevent the spread of pharmaceuticals in the environment.


Anaerobic Digestion Biogas Production Broiler Chicken Dung Beetle Good Management Practice 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Barker AV, Bryson GM (2002) Bioremediation of heavy metals and organic toxicants by composting. ScientificWorldJournal 2:407–420CrossRefGoogle Scholar
  2. Casewell M, Friis C, Marco E, Mcmullin P, Phillips I (2003) The European ban on growth-promoting antibiotics and emerging consequences for human and animal health. J Antimicrob Chemother 52:159–161CrossRefGoogle Scholar
  3. Cox LA, Ricci PF (2008) Causal regulations vs. political will: Why human zoonotic infections increase despite precautionary bans on animal antibiotics. Environ Int 34:459–475CrossRefGoogle Scholar
  4. Dadour IR, Cook DF, Hennessy D (2000) Reproduction and survival of the dung beetle Onthophagus binodis (Coleoptera: Scarabaeidae) exposed to abamectin and doramectin residues in cattle dung. Environ Entomol 29:1116–1122CrossRefGoogle Scholar
  5. Davis JG, Truman CC, Kim SC, Ascough JC, Carlson K (2006) Antibiotic transport via runoff and soil loss. J Environ Qual 35:2250–2260CrossRefGoogle Scholar
  6. Dolliver H, Gupta S (2008) Antibiotic losses in leaching and surface runoff from manure-amended agricultural land. J Environ Qual 37:1227–1237CrossRefGoogle Scholar
  7. Hammerum AM, Heuer OE, Emborg HD, Bagger-Skjot L, Jensen VF, Rogues AM, Skov RL, Agerso Y, Brandt CT, Seyfarth AM, Muller A, Hovgaard K, Ajufo J, Bager F, Aarestrup FM, Frimodt-Moller N, Wegener HC, Monnet DL (2007a) Danish integrated antimicrobial in resistance monitoring and research program. Emerg Infect Dis 13:1632–1639Google Scholar
  8. Hammerum AM, Heuer OE, Lester CH, Agersø Y, Seyfarth AM, Emborg HD, Frimodt-Moller N, Monnet DL (2007b) Comment on: withdrawal of growth-promoting antibiotics in Europe and its effects in relation to human health. Int J Antimicrob Agents 30:466–468CrossRefGoogle Scholar
  9. McBride W, Key N, Mathews KH Jr (2008) Subtherapeutic antibiotics and productivity in U.S. hog production. Rev Agr Econ 30:270–288CrossRefGoogle Scholar
  10. Peak N, Knapp CW, Yang RK, Hanfelt MM, Smith MS, Aga DS, Graham DW (2007) Abundance of six tetracycline resistance genes in wastewater lagoons at cattle feedlots with different antibiotic use strategies. Environ Microbiol 9:143–151CrossRefGoogle Scholar
  11. Pei R, Cha J-M, Carlson KH, Pruden A (2007) Biological treatment of antibiotic resistance genes (ARG) in dairy lagoon water. Environ Sci Technol 41:5108–5113CrossRefGoogle Scholar
  12. Phillips I (2007) Withdrawal of growth-promoting antibiotics in Europe and its effects in relation to human health. Int J Antimicrob Agents 30:101–107CrossRefGoogle Scholar
  13. Smith DJ (2000) Total radioactive residues and clenbuterol residues in swine after dietary administration of [14C]clenbuterol for seven days and preslaughter withdrawal periods of zero, three, or seven days. J Anim Sci 78:2903–2912Google Scholar
  14. Storteboom HN, Kim SC, Doesken K, Davis J, Carlson KH, Pruden A (2007) Response of Antibiotics and Resistance Genes to High-Intensity and Low-Intensity Manure Management. J Environ Qual 36:1695–1703Google Scholar
  15. van den Bogaard AE, Bruinsma N, Stobberingh EE. (2000) The effect of banning avoparcin on VRE carriage in The Netherlands. Journal of Antimicrobial Chemotherapy. 46:146–148Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Departments of Endocrinology and ToxicologyKimron Veterinary InstituteBet DaganIsrael

Personalised recommendations