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Effects of Steroid Hormones on Aquatic and Soil Organisms

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Hormones and Pharmaceuticals Generated by Concentrated Animal Feeding Operations

Part of the book series: Emerging Topics in Ecotoxicology ((ETEP,volume 1))

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Abstract

The naturally occurring steroid hormones are evolutionary old compounds and have documented effects in most phyla. The problem for environmental effects is therefore a matter of determining which effects may have an environmental impact at concentrations released from CAFOs. Of primary concern are the suspected effects on fish reproduction. The effects of steroids on soil organisms may actually increase biomass as steroids can serve as a carbon source.

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References

  • Alon G, Shore LS, Steinberger Y (2007) Correlation between levels of sex hormones (progesterone, testosterone, estrogen) and ecophysiological behavior stages in two species of desert snails (Sphincterochila zonata and Sphincterochila prophetarum) in the northern Negev Desert. Gen Comp Endo 151:122–127

    Article  CAS  Google Scholar 

  • Breskvar K, Ferenčak Z, Hudnik-Plevnik T (1995) The role of cytochrome P45011α in detoxification of steroids in the filamentous fungus Rhizopus nigricans. J Steroid Biochem Mol Biol 52:271–275

    Article  CAS  Google Scholar 

  • Brian JV, Harris CA, Scholze M, Backhaus T, Booy P, Lamoree M, Pojana G, Jonkers N, Runnalls T, Bonfà A, Marcomini A, Sumpter JP (2005) Prediction of the response of freshwater fish to a mixture of estrogenic chemicals. Environ Health Perspect 113:721–728

    Article  CAS  Google Scholar 

  • Chun S, Lee J, Geyer R, White DC, Raman DR (2005) Effect of agricultural antibiotics on the persistence and transformation of 17β-estradiol in a Sequatchie loam. J Environ Sci Health B 40:741–751

    Article  Google Scholar 

  • Chun S, Lee J, Radosevich M, White DC, Geyer RJ (2006) Influence of agricultural antibiotics and 17β-estradiol on the microbial community of soil. Environ Sci Health B 41:923–935

    Article  CAS  Google Scholar 

  • Clemons KV, Stover EP, Schar G, Stathis PA, Chan K, Tokes L, Stevens DA, Feldman D (1989) Steroid metabolism as a mechanism of escape from progesterone-mediated growth inhibition in Trichophyton mentagrophytes. J Biol Chem 264:11186–11192

    CAS  Google Scholar 

  • Custodia N, Won SJ, Novillo A, Wieland M, Li C, Callard IP (2001) Caenorhabditis elegans as an environmental monitor using DNA microarray analysis. Ann NY Acad Sci 948:32–42

    Article  CAS  Google Scholar 

  • Degani G, Boker R, Jackson K (1998) Growth hormone, sexual maturity and steroids in male carp (Cyprinus carpio). Comp Biochem Physiol C 120:433–440

    CAS  Google Scholar 

  • Denslow ND, Leeb HS, Bowmanc CJ, Hemmerd MJ, Folmard LC (2001) Multiple responses in gene expression in fish treated with estrogen. Comp Biochem Physiol B 129:277–282

    Article  CAS  Google Scholar 

  • Dropkin VH, Lower WR, Acedo J (1971) Growth inhibition of Caenorhabditis elegans and Panagrellus redivivus by selected mammalian and insect hormones. J Nematol 3:349–355

    CAS  Google Scholar 

  • Folmar LC, Hemmer M, Hemmer R, Bowman C, Kroll K, Denslow ND (2000) Comparative estrogenicity of estradiol, ethynylestradiol and diethylstilbestrol in an in vivo, male sheepshead minnow (Cyprinodon variegatus), vitellogenin bioassay. Aquat Toxicol 49:77–88

    Article  CAS  Google Scholar 

  • Fox JE, Starcevic M, Jones PE, Burow ME, McLachlan JA (2004) Phytoestrogen signaling and symbiotic gene activation are disrupted by endocrine-disrupting chemicals. Environ Health Perspect 112:672–677

    Article  CAS  Google Scholar 

  • Hoshi H, Kamata Y, Uemura T (2003) Effects of 17β-estradiol, bisphenol A and tributyltin chloride on germ cells of Caenorhabditis elegans. J Vet Med Sci 65:881–885

    Article  CAS  Google Scholar 

  • Höss S, Weltje L (2007) Endocrine disruption in nematodes: effects and mechanisms Ecotoxicology 16:15–28

    Google Scholar 

  • Howell WM, Black DA, Bortone SA (1980) Abnormal expression of secondary sex characters in a population of mosquitofish, Gambusia affinis holbrooki: evidence for environmentally-induced masculinization. Copeia 1980:676–681

    Article  Google Scholar 

  • Huggert DB, Ericson JF, Cook JC, Williams RT (2004) In: Kümmerer K (ed) Pharmaceuticals in the environment. Sources, fate, effects and risks, 2nd edn. Springer-Verlag, Heidelberg Berlin pp 373–386

    Google Scholar 

  • Jobling S, Nolan M, Tyler CR, Brighty GC, Sumpter JP (1998) Widespread sexual disruption in wild fish. Environ Sci Technol 32:2498–2506

    Article  CAS  Google Scholar 

  • Koger CS, Teh SJ, Hinton DE (2000) Determining the sensitive developmental stages of intersex induction in medaka (Oryzias latipes) exposed to 17ß-estradiol or testosterone. Marine Environ Res 50:201–206

    Article  CAS  Google Scholar 

  • Kramer VJ, Miles-Richardson S, Pierens SL, Giesy GP (1998) Reproductive impairment and induction of alkaline-labile phosphate, a biomarker of estrogen exposure, in fathead minnows (Pimephales promelas) exposed to waterborne 17β-estradiol. Aquat Toxicol 40:335–360

    Article  CAS  Google Scholar 

  • Krisfalusi M, Nagler JJ (2000) Induction of gonadal intersex in genotypic male rainbow trout (Oncorhynchus mykiss) embryos following immersion in estradiol-17ß. Mol Reprod Dev 56:495–501

    Article  CAS  Google Scholar 

  • Larsson DGJ, Erici MA, Parkkonen J, Pettersson M, Berg AH, Olsson PE, Forlin L (1999) Ethinyloestradiol - An undesired fish contraceptive? Aquat Toxicol 45:91–97

    Article  CAS  Google Scholar 

  • Markman S, Guschina IA, Barnsley S, Buchanan KL, Pascoe D, Müller CT (2007) Endocrine disrupting chemicals accumulate in earthworms exposed to sewage effluent. Chemosphere 70:119–125

    Article  CAS  Google Scholar 

  • Metcalfe CD, Metcalfe TL, Kiparissis Y, Koenig BG, Khan C, Hughes RJ, Croley TR, March RE, Potter T (2001) Estrogenic potency of chemicals detected in sewage treatment plant effluents as determined by in vivo assays with Japanese medaka (Oryzias latipes). Environ Toxicol Chem 20:297–308

    CAS  Google Scholar 

  • Mimoto A, Fujii M, Usami M, Shimamura M, Hirabayashi N, Kaneko T, Sasagawa N, Ishiura S (2007) Identification of an estrogenic hormone receptor in Caenorhabditis elegans. Biochem Biophy Res Commun 364:883–888

    Article  CAS  Google Scholar 

  • Möbus E, Jahn M, Schmid R, Jahn D, Maser E (1997) Testosterone-regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni. J Bacteriol 179:5951–5955

    Google Scholar 

  • Nakamura M (1984) Effects of estradiol-17β on gonadal sex differentiation in two species of salmonids, the masu salmon, Oncorhynchus masou, and the chum salmon. O. keta. Aquaculture 43:83–90

    Article  CAS  Google Scholar 

  • Nash JP, Kime DE, Van der Ven LTM, Wester PW, Brion F, Maack G (2004) Long-term exposure to environmental concentrations of the pharmaceutical ethynylestradiol causes reproductive failure in fish. Environ Health Perspect 112:1725–1733

    Article  CAS  Google Scholar 

  • Oehlmann J, Schulte-Oehlmann U (2003) Endocrine disruption in invertebrates. Pure Appl Chem 75:2207–2218

    Article  CAS  Google Scholar 

  • Oehlmann J, Di Benedetto P, Tillmann M, Duft M, Oetken M, Schulte-Oehlmann U (2007) Endocrine disruption in prosobranch molluscs: evidence and ecological relevance. Ecotoxicology 16:29–43

    Article  CAS  Google Scholar 

  • Panter GH, Thompson RS, Sumpter JP (1998) Adverse reproductive effects in male fathead minnows (Pimephles promelas) exposed to environmentally relevant concentrations of the natural oestrogens, oestradiol and oestrone. Aquat Toxicol 42:243–253

    Article  CAS  Google Scholar 

  • Purdam CE, Hardiman PA, Bye VJ, Eno NC, Tyler CR, Sumpter JP (1994) Estrogenic effects of effluent from sewage treatment works. Chem Ecol 8:275–285

    Article  Google Scholar 

  • Rose J, Holbech H, Lindholst C, Norum U, Povlsen A, Korsgaard B, Bjerregaard P (2000) Vitellogenin induction by 17β-estradiol and 17α-ethinylestradiol in male zebrafish (Danio rerio). Comp Biochem Physiol C 131:531–539

    Google Scholar 

  • Routledge EJ, Sheahan D, Desbrow GC, Brighty M, Waldock M, Sumpter JP (1998) Identification of estrogenic chemicals in STW effluent. 2. In vivo responses in trout and roach. Environ Sci Technol 32:1559–1565

    Article  CAS  Google Scholar 

  • Shore LS, Kapulnik Y, Ben-Dov B, Fridman Y, Wininger S, Shemesh M (1992) Effects of estrone and 17ß-estradiol on vegetative growth of Medicago sativa. Physiol Plant 84:217–222

    Article  CAS  Google Scholar 

  • Shore LS, Gurevich M, Shemesh M, (1993) Estrogen as an environmental pollutant. Bull Environ Contam Toxicol 51:361–366

    Article  CAS  Google Scholar 

  • Shore LS, Kapulnik Y, Gurevich M, Wininger S, Badamy H, Shemesh M (1995) Induction of phytoestrogens production in Medicago sativa leaves by irrigation with sewage water. Environ Exp Bot 35:363–369

    Article  Google Scholar 

  • Shore LS, Cuneah O, Barel-Cohen K (2007) Concentrations of androstenedione and testosterone in manure, effluent, soil and surface water. In:Proceedings of the 6th international conference on pharmaceuticals and EDC chemicals in water. http://ngwa.confex.com/ngwa/pharm6/techprogram/S2007.HTM

  • Sumpter JP (1995) Feminized responses in fish to environmental estrogens. Toxicol Lett 82(83):737–742

    Article  Google Scholar 

  • Sumpter JP, Jobling S (1995) Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ Health Perspect 103:173–178

    CAS  Google Scholar 

  • Thong CHS, Webster JM (1971) The effect of gonadotrophins on the in vitro growth of the free-living nematode Cephalobus sp. Bastian. Can J Zool 49:1059–1061

    Article  CAS  Google Scholar 

  • Thorpe KL, Benstead R, Hutchinson TH, Cummings RI, Tyler CR (2003) Reproductive effects of exposure to oestrone in the fathead minnow. Fish Physiol Biochem 28:451–452

    Article  CAS  Google Scholar 

  • Tominaga N, Tomoeda M, Kohra S, Takao Y, Nagae M, Ueda K, Ishibashi H, Kai T, Arizono K (2002) A convenient sublethal assay of alkylphenol and organotin compounds using the nematode Caenorhabditis elegans. J Health Sci 48:555–559

    Article  CAS  Google Scholar 

  • Van den Belt K, Berckmans P, Vangenechten C, Verheyen R, Witters H (2004) Comparative study on the in vitro/in vivo estrogenic potencies of 17β-estradiol, estrone, 17α-ethynylestradiol and nonylphenol. Aquat Toxicol 66:183–195

    Article  Google Scholar 

  • Vitas M, Smith KE, Plavec J, Kesselmeier J, Pajič T, Ferlan A, Žigon D, Kelly SL, Komel R (1999) Induction of steroidal hydroxylase activity by plant defence compounds in the filamentous fungus Cochliobolus lunatus. Chemosphere 38:853–863

    Article  CAS  Google Scholar 

  • Wang R, Belosevic M (1994) Estradiol increases susceptibility of goldfish to Trypanosoma danilewskyi. Dev Comp Immunol 18:377–387

    Article  CAS  Google Scholar 

  • Webb SF (2004) A data based perspective on the environmental risk assessment of human pharmaceuticals III- indirect human exposure. In: Kümmerer K (ed) Pharmaceuticals in the environment. Sources, fate, effects and risks, 2nd edn. Springer-Verlag, Heidelberg Berlin pp 373–386

    Google Scholar 

  • Woo NYS, Chung ASB, Ng TB (1993) Influence of oral administration of estradiol-17β and testosterone on growth, digestion, food conservation and metabolism in the underyearling red sea bream, Chrysophrys major. Fish Physiol Biochem 10:377–387

    Article  CAS  Google Scholar 

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  1. Departments of Endocrinology and Toxicology, Kimron Veterinary Institute, POB 12, Bet Dagan, 50250, Israel

    Laurence Shore

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    Shore, L. (2009). Effects of Steroid Hormones on Aquatic and Soil Organisms. In: Pruden, A., Shore, . (eds) Hormones and Pharmaceuticals Generated by Concentrated Animal Feeding Operations. Emerging Topics in Ecotoxicology, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-0-387-92834-0_11

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