ICG Clearance Monitoring in ICU Patients

  • E. Levesque
  • F. Saliba


Indocyanine green (ICG) clearance has been used, since the 1950s, as an indicator of dynamic liver function. The emergence of static liver function tests together with imaging and histology, has reduced the use of ICG measurements in the clinical setting. During the last two decades, methods to assess the hepatosplanchnic circulation and liver function have been the focus of intense investigation. The monitoring of this regional circulation has been shown to be the best predictor of outcome in critically ill patients [1]. As technologies advance, two mains goals can be identified concerning hemodynamic monitoring: The first is to make measurements using non-invasive tools in order to eliminate the risks associated with invasive monitoring; the second is to find a single measurement that could predict patient status. The same points are currently needed in regional hemodynamic monitoring. This chapter briefly considers ICG clearance physiology and its various methods of measurement, reviews the indications for ICG clearance measurement, and defines the current interests and limits of this technique with regard to hepatic functional impairment in critically ill patients with sepsis, liver disease, or after major hepatic surgery and liver transplantation.


Liver Transplantation Intensive Care Unit Patient Indocyanine Green Hepatic Blood Flow Hepatic Artery Thrombosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • E. Levesque
    • 1
  • F. Saliba
    • 2
  1. 1.Department of Intensive CareHôpital Paul BrousseVillejuifFrance
  2. 2.Hepatobiliary CenterHôpital Paul BrousseVillejuifFrance

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