Post-pneumonectomy Pulmonary Edema

  • D. Cook
  • E. Powell
  • F. Gao-Smith


The first successful pneumonectomy was performed as a two step procedure by Rudolf Nissen in 1930. Although lesser resections are now performed when possible, in certain cases of non-small cell lung cancer, pneumonectomy provides the only potentially curative option. However, it is a procedure associated with a high mortality (3.3–9.3 %) and morbidity (30.6–59 %) [1, 2, 3, 4, 5]. Post-pneumonectomy pulmonary edema is not an infrequent complication of pneumonectomy (incidence 4–7 %) [6] and one that is associated with a mortality of at least 50 % [7]. Post-pneumonectomy pulmonary edema is often called post-lung resection acute lung injury, firstly due to its pathophysiological and clinical similarities to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), and secondly because it occurs following lobectomy as well as pneumonectomy. This chapter outlines the diagnosis and prevalence of this condition and then discusses the potential etiological factors.


Pulmonary Edema Acute Lung Injury Acute Respiratory Distress Syndrome Respir Crit Fresh Freeze Plasma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • D. Cook
    • 1
  • E. Powell
    • 1
  • F. Gao-Smith
    • 1
  1. 1.Department of Anesthesia, Critical Care and PainBirmingham Heartlands HospitalBirminghamUK

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