Patient-ventilator Interaction during Non-invasive Ventilation

  • P. Jolliet
  • D. Tassaux
  • L. Vignaux


Over the years, non-invasive ventilation (NIV) has evolved into becoming a standard of care in both hypercapnic and non-hypercapnic acute respiratory failure [1, 2, 3]. However, its success in avoiding intubation is largely determined by patient tolerance to the technique [4]. The optimal combination of the patient’s spontaneous breathing activity and the ventilator’s set parameters, known as ‘patient-ventilator interaction’, depends on numerous factors, and can prove very difficult to achieve [5, 6]. If patient ventilator asynchrony is present, the work of breathing can increase [5, 6]. Further complicating the matter, leaks at the patient-mask interface during NIV can interfere with various aspects of ventilator function, thereby increasing the risk of patient-ventilator asynchrony [7, 8, 9, 10]. As an illustration, a recent study documented that severe asynchrony was present in 43 % of patients undergoing NIV for acute respiratory failure [11]. Consequently, when applying NIV the clinician must pay close attention to both the proper setting of ventilator parameters and the avoidance of excessive leaks at the patient-mask interface.


Acute Respiratory Failure Pressure Support Respir Crit Pressure Support Ventilation Noninvasive Ventilation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • P. Jolliet
    • 1
  • D. Tassaux
    • 1
  • L. Vignaux
    • 1
  1. 1.Department of Intensive CareUniversity HospitalGeneva 14Switzerland

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