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Lung Proteomics in Intensive Care

  • Conference paper
Intensive Care Medicine

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Abstract

The advent of routinely available genomics and sequencing of the human genome, among others, associated with advances in technology previously limited to biochemical research, and in bioinformatics has brought the new field of proteomics within the reach of the life sciences and even clinical research. Important hypotheses are increasingly being generated in lung disease by biomarker identification from screening of clinical samples. However, proteomics, ideally suited for biomarker discovery, is only just emerging as a field of research in intensive care and has, to date, mostly been applied to serumin studies of sepsis [1–5]. The purpose of this chapter is to overview the rationale, basics, methods, pitfalls, applications, and future directions for lung proteomics in intensive care.

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Author information

Authors and Affiliations

  1. Department of Surgical Intensive Care Hôpital Huriez Centre Hospitalier Régional, Universitaire de Lille, 1 rue Michel Polonovski, 59037, Lille, France

    E. Kipnis

  2. Cancer Center Proteomics Core, University of Colorado Denver, UCD Anschutz Medical Campus, RC-1 South, L18-1303, PO Box 6511, Campus Box 8119, Aurora, CO, 80045, USA

    K. Hansen

Authors
  1. E. Kipnis
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  2. K. Hansen
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Universitée libre de Bruxelles, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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© 2009 Springer-Verlag Berlin Heidelberg

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Kipnis, E., Hansen, K. (2009). Lung Proteomics in Intensive Care. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-92278-2_3

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  • DOI: https://doi.org/10.1007/978-0-387-92278-2_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-92277-5

  • Online ISBN: 978-0-387-92278-2

  • eBook Packages: MedicineMedicine (R0)

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