Developmental Aspects of Health Related Quality of Life (HRQL) in Food Related Chronic Disease: The Example of Food Allergy

  • Audrey DunnGalvin
  • Jonathan O’B. Hourihane


Health related quality of life (HRQL) measures provide a powerful means of measuring outcomes, enabling service providers in the clinical field to audit ‘outcome’ information for particular populations, thereby altering and improving resources and programmes, and prioritizing needs. However, there are important questions that must be answered before HRQL measures can reach their full potential in research, practice and policy. One of the most important concerns the impact of developmental processes on HRQL perception, impact and health outcomes. In this chapter, using food allergy as an example, we review research on health related quality of life in children, teens and parents. We draw on neurobiological literature in allergic diseases, in addition to some of the key psychobiological theories in the current work on threat perception in health to argue for a broader understanding of HRQL. This review also aims to provide a scientific basis for the development of appropriate models linking symptoms, functioning, development, underlying physiological mechanisms and HRQOL. An integrated developmental perspective may also illuminate our understanding of individual differences in the expression and impact of chronic diseases involving diet and food. The implications of this developing field of research are enormous with implications for the interpretation and usefulness of HRQL measures and its application to clinical practice, health policy, cause and effect pathways, the development of psycho-educational interventions and the precise targeting of information.


Food Allergy Food Challenge Peanut Allergy Food Allergic Child Enable Service Provider 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Health Related Quality of Life


Food Allergy Quality of Life Questionnaire


Parent Form


Food Allergy Independent Measure


Oral Immunotherapy



This work was funded by the EU through the EuroPrevall project (FOOD-CT-2005-514000).


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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Clinical Investigations Unit, Department of Paediatrics and Child Health, Cork University HospitalUniversity College Cork (UCC)CorkIreland

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