Carbohydrates pp 143-167 | Cite as

Cyclic Acetals and Ketals



Cyclic and acyclic carbohydrates react with aldehydes and/or ketones, in the presence of catalysts (hard or Lewis acids), to give cyclic acetals and/or ketals (1,3-dioxolanes 3 or 1,3-dioxanes 5, respectively) (Fig. 6.1 ). This reaction is routinely used in carbohydrate chemistry for the protection of hydroxyl groups in a sugar in order to prevent their interference in chemical transformation(s) of other hydroxyl group(s) of that sugar.


Concentrate Sulfuric Acid Zinc Chloride Cyclic Acetal Triphenyl Phosphite Acetal Carbon 


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Authors and Affiliations

  1. 1.Department of Biochemistry & Molecular BiologyPennsylvania State UniversityHersheyUSA

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