Carbohydrates pp 423-467 | Cite as

Synthesis of Polychiral Natural Products from Carbohydrates

  • Momcilo Miljković


Stereoselective synthesis of polychiral natural products is the most challenging problem for a synthetic organic chemist. The stereoselective synthesis of macrolide antibiotics represents one such difficult problem. They consist of macrocyclic lactone rings with many hydroxylated and methylated chiral carbons. In addition to that the macrocyclic lactones (macrolides) are usually glycosylated with amino sugars.


Methyl Ketone Stereoselective Synthesis Anomeric Configuration Pyridinium Chlorochromate Phenyl Sulfone 
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Authors and Affiliations

  1. 1.Department of Biochemistry & Molecular BiologyPennsylvania State UniversityHersheyUSA

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