The methods discussed in Chap. 4 all rely on the assumption that, given QTL genotype, the phenotype follows a normal distribution. This is not the same as to assume that the marginal phenotype distribution is normal—it will follow a mixture of normal distributions. But in the case that no QTL has very large effect, the marginal phenotype distribution would generally be close to normal: unimodal and reasonably symmetric.
KeywordsInterval Mapping Binary Trait Survival Package Argument Model Interval Mapping Method
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