Case study II

  • Karl W. Broman
  • Śaunak Sen
Part of the Statistics for Biology and Health book series (SBH)

In this chapter, we present a second case study. This case study illustrates an investigation of interactions between QTL and a covariate. It also shows how we may deal with genotype data organized in linkage groups (as opposed to chromosomes). Data of that type are rare for established model organisms, but common for emerging ones without extensive genomic resources. As with the case study in Chap. 10, there are some unusual features here, but most QTL analyses will be unusual in one way or another.


Linkage Group Marker Genotype Data Model Comparison Criterion Estimate Recombination Fraction Multiple Linkage Group 
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Copyright information

© Springer-Verlag New York 2009

Authors and Affiliations

  1. 1.Dept. Biostatistics & Medical InformaticsUniversity of Wisconsin-MadisonMadisonUSA
  2. 2.Dept. Epidemiology & BiostatisticsUniversity of California San FranciscoSan FranciscoUSA

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