A 4-year-old boy presented with anemia and thrombocytopenia. Physical examination revealed moderate splenomegaly and mild hepatomegaly. His liver enzymes were slightly elevated. A thorough neurologic examination did not show any abnormality. The splenectomy specimen showed marked expansion of the red pulp cords by histiocytes with fibrillary cytoplasm (Figs. 84.1, 84.2, and 84.3). A bone marrow biopsy revealed infiltration with the same histiocytes (Figs. 84.4 and 84.5).


Chronic Myeloid Leukemia Bone Marrow Biopsy Gauche Disease Lysosomal Storage Disease Gauche Cell 
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