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A 59-year-old man presented with splenomegaly and lymphadenopathy in the inguinal region. Hypersplenism was manifested as anemia and thrombocytopenia. The splenectomy specimen showed many foam histiocytes (Fig. 83.1). The lymph node biopsy also showed accumulation of similar histiocytes (Fig. 83.2).

Keywords

Gauche Disease Central Nervous System Involvement Hematologic Neoplasm Neonatal Jaundice Acid Sphingomyelinase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Kolodny ED. Niemann-Pick disease. Curr Opin Hematol 2007;7:48–52.CrossRefGoogle Scholar
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    Nieman RS, Orazi A. Disorders of the spleen. 2nd ed., Philadelphia, W.B. Saunders, 1999, 171.Google Scholar

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© Springer Science+Business Media, LLC 2009

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