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A 59-year-old man presented with splenomegaly and lymphadenopathy in the inguinal region. Hypersplenism was manifested as anemia and thrombocytopenia. The splenectomy specimen showed many foam histiocytes (Fig. 83.1). The lymph node biopsy also showed accumulation of similar histiocytes (Fig. 83.2).

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References

  1. Kolodny ED. Niemann-Pick disease. Curr Opin Hematol 2007;7:48–52.

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  2. Cruse RP. Overview of Niemann-Pick disease. UpToDate online15.3, 2007.

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  3. Nieman RS, Orazi A. Disorders of the spleen. 2nd ed., Philadelphia, W.B. Saunders, 1999, 171.

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© 2009 Springer Science+Business Media, LLC

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(2009). Case 83. In: Sun, T. (eds) Atlas of Hematologic Neoplasms. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-89848-3_84

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  • DOI: https://doi.org/10.1007/978-0-387-89848-3_84

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-89847-6

  • Online ISBN: 978-0-387-89848-3

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