A 59-year-old man presented with splenomegaly and lymphadenopathy in the inguinal region. Hypersplenism was manifested as anemia and thrombocytopenia. The splenectomy specimen showed many foam histiocytes (Fig. 83.1). The lymph node biopsy also showed accumulation of similar histiocytes (Fig. 83.2).
KeywordsGauche Disease Central Nervous System Involvement Hematologic Neoplasm Neonatal Jaundice Acid Sphingomyelinase
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