A 64-year-old man presented with fever, chills, night sweats, and weight loss for one week. Physical examination showed generalized peripheral lymphadenopathy and splenomegaly. Laboratory studies revealed neutrophilia and lymphopenia, elevated lactate dehydrogenase and polyclonal hypergammaglobulinemia. A biopsy of the right cervical lymph node was performed (Figs. 64.1, 64.2, 64.3, and 64.4).


Latent Membrane Protein Autoimmune Hemolytic Anemia Large Tumor Cell Polyclonal Hypergammaglobulinemia Angioimmunoblastic Lymphadenopathy 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Dogan A, Gaulard P, Jaffe ES, et al. Angioimmunoblastic T-cell lymphoma. In Swerdlow SH, Campo E, Harris NL, et al. eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th ed., Lyon, France, IARC Press, 2008; 309–311.Google Scholar
  2. 2.
    Dogan A, Attygalle AD, Kyriakou C. Angioimmunoblastic T-cell lymphoma. Br J Haematol 2003;121:681–691.CrossRefPubMedGoogle Scholar
  3. 3.
    Ferry JA. Angioimmunoblastic T-cell lymphoma. Adv Anat Pathol 2002;9:273–279.CrossRefPubMedGoogle Scholar
  4. 4.
    Attygalle A, Al-Jehani R, Diss T, et al. Neoplastic T cells in angioimmunoblastic T-cell lymphoma express CD10. Blood 2002;99:627–633.CrossRefPubMedGoogle Scholar
  5. 5.
    Dogan A, Morice WG.. Bone marrow histopathology in peripheral T-cell lymphomas. Br J Haematol 2004;127:140–154.CrossRefPubMedGoogle Scholar
  6. 6.
    Dunleavy K, Wilson WH, Jaffe ES. Angioimmunoblastic T cell lymphoma: pathobiological insights and clinical implications. Curr Opin Hematol 2007;14:348–353.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Personalised recommendations