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A 39-year-old man presented with progressive skin lesions on his trunk associated with constitutional symptoms for six months. He had arthralgias, bone pain in the ankles and wrists, fatigue, fever, and a 20-pound weight loss over a period of six months. He was treated with a short course of antibiotics without benefit. Physical examination revealed diffused subcutaneous nodules of varying sizes over his trunk with the largest nodule measuring 4 cm. Lymphadenopathy and hepatosplenomegaly were not detected. Laboratory test results, including liver function tests and hematology workup, were within normal ranges. A skin biopsy showed tumor cell infiltration (Figs. 61.1 and 61.2). Subsequently, a bone marrow biopsy was performed (Figs. 61.3 and 61.4).

Keywords

Plasmacytoid Dendritic Cell Blastic Plasmacytoid Dendritic Cell Neoplasm Include Liver Function Test Dendritic Cell Neoplasm Immunoglobulin Heavy Chain Gene Rearrangement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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