A 39-year-old man presented with progressive skin lesions on his trunk associated with constitutional symptoms for six months. He had arthralgias, bone pain in the ankles and wrists, fatigue, fever, and a 20-pound weight loss over a period of six months. He was treated with a short course of antibiotics without benefit. Physical examination revealed diffused subcutaneous nodules of varying sizes over his trunk with the largest nodule measuring 4 cm. Lymphadenopathy and hepatosplenomegaly were not detected. Laboratory test results, including liver function tests and hematology workup, were within normal ranges. A skin biopsy showed tumor cell infiltration (Figs. 61.1 and 61.2). Subsequently, a bone marrow biopsy was performed (Figs. 61.3 and 61.4).
KeywordsPlasmacytoid Dendritic Cell Blastic Plasmacytoid Dendritic Cell Neoplasm Include Liver Function Test Dendritic Cell Neoplasm Immunoglobulin Heavy Chain Gene Rearrangement
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