A 79-year-old man presented with pleural effusion with dyspnea on exertion for three months. These symptoms were attributed to congestive heart failure after myocardial infarction. Pleural fluid showed WBC 6700/μl with 62% lymphocytes. Physical examination revealed no peripheral lymphadenopathy and no hepatosplenomegaly. CT and MRI showed no lymphadenopathy and organomegaly in the thoracic and abdominal cavities. Bilateral bone marrow biopsy was negative for lymphoma. The patient had no risk factors for acquired immunodeficiency syndrome (AIDS). Cytospin smear and cell block of the pleural fluid demonstrated large pleomorphic tumor cells (Figs. 52.1, 52.2, 52.3, and 52.4).


Pleural Fluid Giant Tumor Cell Anaplastic Large Cell Lymphoma Cell Block Primary Effusion Lymphoma 
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