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A 7-year-old boy presented with dyspnea, cough and wheezing for two weeks. He was treated for asthma, with no effect. Chest X-ray examination demonstrated a large anterior mediastinal mass. Physical examination revealed facial edema and palpable cervical and axillary lymph nodes. There was no hepatosplenomegaly. Examination of the peripheral blood showed mild anemia with normal leukocyte and platelet counts. A mediastinal biopsy was obtained through mediastinoscopy (Figs. 25.1 and 25.2).

Keywords

Terminal Deoxynucleotidyl Transferase Burkitt Lymphoma Mediastinal Mass Superior Vena Cava Syndrome Flow Cytometric Histogram 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Borowitz M, Chan JKC. T lymphoblastic leukaemia/lymphoma. In Swerdlow SH, Campo E, Harris NL, et al. eds. WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues. 4th ed., Lyon, France, IARC Press, 2008, 176–178.Google Scholar
  2. 2.
    Uyttebroeck A, Vanhentenrijk V, Hagemeijer A, et al. Is there a difference in childhood T-cell acute lymphoblastic leukaemia and T-cell lymphoblastic lymphoma? Leuk Lymphoma 2007;48:1745–1754.CrossRefPubMedGoogle Scholar
  3. 3.
    Ellison DA, Parham DM, Sawyer JR. Cytogenetic findings in pediatric T-lymphoblastic lymphomas: One institution’s experience and a review of the literature. Pediatr Devel Pathol 2005;8:550–556.CrossRefGoogle Scholar
  4. 4.
    Raetz EA, Perkins SL, Bhojwani D, et al. Gene expression profiling reveals intrinsic differences between T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. Pediatr Blood Cancer 2006;47:130–140.CrossRefPubMedGoogle Scholar
  5. 5.
    Sun T. Flow Cytometry and Immunohistochemistry for Hematologic Neoplasms. Philadelphia, Lippincott Williams & Wilkins, 2008, 143–151.Google Scholar

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© Springer Science+Business Media, LLC 2009

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