Common Problems in Orthopedic Pathology Including Trauma, Reactive Conditions and Necrosis of Bone



The pathology and pathophysiology of bone healing is important from several aspects. For the surgical pathologist, it is critical to be able to distinguish normal fracture healing in bone from disordered healing and from bone neoplasms. For the orthopedic surgeon and the scientific investigator, the histologic appearances of healing allow a qualitative and quantitative assessment of the process. This permits, for example, the comparison of different methods of treatment. Additionally, an understanding of the cellular signals operating in bone healing, allows the clinician to manipulate and promote or modify osseous union.


Femoral Head Sickle Cell Disease Heterotopic Ossification Bone Marrow Edema Distraction Osteogenesis 

Suggested Readings

  1. Pathology of Bone and Joint Disorders with Clinical and Radiographic Correlation, Edward F. McCarthy and Frank J. Frassica. W.B. Saunders, 1998Google Scholar
  2. Orthopaedic Pathology, Vincent J. Vigorita. Lippincott Williams and Wilkins (Wolters Kluwer), 2007Google Scholar
  3. Bone Pathology, Jasvir S. Khurana. Humana Press, 2009Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Temple University HospitalPhiladelphiaUSA
  2. 2.Johns Hopkins HospitalBaltimoreUSA

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