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Large Cell Carcinoma

  • Armin Ernst
  • Philip T. Cagle
  • Timothy C. Allen
  • Dina R. Mody
  • Armando E. Fraire
Chapter

Abstract

This carcinoma represents about 10% of all lung cancers. Microscopically, its main feature is the high level of malignancy and lack of squamous or glandular features. However, on electron microscopy, features of either adenocarcinoma or squamous cell can be appreciated suggesting that large cell carcinomas are basically poorly differentiated adenocarcinomas or squamous cell carcinomas. Nonetheless, the clinical presentation and the radiographic appearance more closely resemble adenocarcinoma. The endoscopic appearance is not distinctive since most large cell carcinomas do not involve the proximal airways. Most present as fleshy hemorrhagic-looking masses such as those shown in this chapter.

Keywords

Small Cell Carcinoma Large Cell Carcinoma Endoscopic Appearance Large Cell Neuroendocrine Carcinoma Proximal Airway 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Armin Ernst
    • 1
  • Philip T. Cagle
    • 2
  • Timothy C. Allen
    • 3
  • Dina R. Mody
    • 4
  • Armando E. Fraire
    • 5
  1. 1.Harvard Medical School, The Beth Israel Deaconess Medical CenterBostonUSA
  2. 2.Weill Medical College, The Methodist Hospital, Cornell UniversityHoustonUSA
  3. 3.The University of Texas Health Science Center at TylerTylerUSA
  4. 4.Weill Medical College, The Methodist Hospital, Cornell UniversityHoustonUSA
  5. 5.University of Massachusetts Medical SchoolWorcesterUSA

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