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Genes, Environment, and Cancer Disparities

  • Alexandra E. Shields
  • Stephanie M. Fullerton
  • Kenneth Olden
Chapter

Eliminating health disparities is a national priority, as reflected in numerous federal initiatives (Institute of Medicine 2002; Kaiser Commission on Medicaid and the Uninsured 2003; Mayberry et al. 2000). The IOM “Crossing the Quality Chasm” (Institute of Medicine 2001) report cited the elimination of health disparities as one of its six priority goals for improving the quality of health care in the US, while the subsequent IOM report, “Unequal Treatment,” provided exhaustive documentation of racial/ethnic health disparities across a wide range of health care settings, diseases (including cancer), and clinical settings (Institute of Medicine 2002). Healthy People 2010 named the elimination of health disparities as one of two primary national goals for improving the health of Americans and explicitly called for reducing the number of new cancer cases as well as the illness, disability, and death caused by cancer (US Department of Health and Human Services 2000).

Keywords

Cancer Risk Environmental Exposure Health Disparity Cancer Susceptibility Environmental Risk Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The authors would like to thank Sharon Kardia, Nick Patterson, and David Christiani for critical comments on earlier drafts of this manuscript. Richard Kwong, Rosemarie Ramos, and Sara Weiner provided excellent research assistance. This chapter was supported by NIH grant NHGRI P20 HG003400 (AS) and the Disparities Program of the Dana-Farber/Harvard Cancer Center. SMF is supported, in part, by a grant to the Center for Genomics and Healthcare Equality (P50HG003374, National Human Genome Research Institute, Wylie Burke, PI).

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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Alexandra E. Shields
    • 1
  • Stephanie M. Fullerton
    • 2
  • Kenneth Olden
    • 3
  1. 1.Harvard/MGH Center on Genomics, Vulnerable Populations, and Health Disparities, and Institute for Health Policy, Massachusetts General Hospital/Partners HealthCareDepartment of MedicineBostonUSA
  2. 2.Department of Medical History and Ethics and Center for Genomics and Healthcare EqualityUniversity of WashingtonWashingtonUSA
  3. 3.Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health SciencesNational Institutes of HealthNorth CarolinaUSA

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