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Surveillance of Antibiotic Resistance in Developing Countries: Needs, Constraints and Realities

  • E. Vlieghe
  • A.M. Bal
  • I. M. Gould
Chapter

Abstract

Surveillance for antimicrobial resistance is important in terms of defining prevention and treatment strategies. While surveillance is routinely and efficiently carried out in developed countries, several major constraints often make it impossible for developing countries to carry out major surveillance programmes in this field. This chapter reviews the problems faced by the developing world in carrying out effective surveillance for antibiotic resistance and briefly describes the available data.

Keywords

Antimicrobial Resistance Surveillance Data Typhoid Fever Resistance Data High Resistance Rate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Adegbola, R.A., Hill, P.C., Secka, O., et al. 2006. Serotype and antimicrobial susceptibility patterns of isolates of Streptococcus pneumoniae causing invasive disease in The Gambia 1996–2003. Trop Med Intl Health 11: 1128–1135.CrossRefGoogle Scholar
  2. Aires De Sousa, M., Santos Sanches, I., Ferro, M.L., De Lencastre, H. 2000. Epidemiological study of staphylococcal colonization and cross-infection in two West African Hospitals. Microb Drug Resist 6: 133–141.CrossRefPubMedGoogle Scholar
  3. Amir, M., Paul, J., Batchelor, B. et al. 1995. Nasopharyngeal carriage of Staphylococcus aureus and carriage of tetracycline-resistant strains associated with HIV-seropositivity. Eur J Clin Microbiol Infect Dis 14: 34–40.CrossRefPubMedGoogle Scholar
  4. Archibald, L.K., Reller, L.B. 2001. Clinical microbiology in developing countries. Emerg Infect Dis 7: 302–305.CrossRefPubMedGoogle Scholar
  5. Bell, J.M., Turnidge, J.D., Jones, R.N. et al. 2002a. Antimicrobial resistance trends in community-acquired respiratory tract pathogens in the Western Pacific Region and South Africa: report from the SENTRY antimicrobial surveillance program, (1998–1999) including an in vitro evaluation of BMS284756. Int J Antimicrob Agents 19: 125–132.CrossRefPubMedGoogle Scholar
  6. Bell, J.M., Turnidge, J.D., Gales, A.C. et al. 2002b. Prevalence of extended spectrum beta-lactamase (ESBL)-producing clinical isolates in the Asia-Pacific region and South Africa: regional results from SENTRY Antimicrobial Surveillance Program (1998–99). Diagn Microbiol Infect Dis 42: 193–198.CrossRefPubMedGoogle Scholar
  7. Bell, J.M., Turnidge, J.D., Jones, R.N. et al. 2003. Prevalence of extended-spectrum beta-lactamase-producing Enterobacter cloacae in the Asia-Pacific region: results from the SENTRY Antimicrobial Surveillance Program, 1998–2001. javascript:AL_get(this, ‘jour’, ‘Antimicrob Agents Chemother.’); Antimicrob Agents Chemother 47: 3989–3993.CrossRefPubMedGoogle Scholar
  8. Blomberg, B., Mwakagile, D.S., Urassa, W.K., et al. 2004. Surveillance of antimicrobial resistance at a tertiary hospital in Tanzania. BMC Public Health 4: 45.CrossRefPubMedGoogle Scholar
  9. Blomberg, B., Olsen, B.E., Hinderaker, S.G. et al. 2005. Antimicrobial resistance in urinary bacterial isolates from pregnant women in rural Tanzania: implications for public health. Scand J Infect Dis 37: 262–268.CrossRefPubMedGoogle Scholar
  10. Borg, M.A., Scicluna, E., de Kraker, M., et al. 2006. Antibiotic resistance in the southeastern Mediterranean – preliminary results from the ARMed project. Euro Surveill 11: 164–167.PubMedGoogle Scholar
  11. Bouchillon, S.K., Johnson, B.M., Hoban, D.J. et al. 2004. Determining incidence of extended spectrum beta-lactamase producing Enterobacteriaceae, vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus in 38 centres from 17 countries: the PEARLS study 2001–2002. Int J Antimicrob Agents 24: 119–124.CrossRefPubMedGoogle Scholar
  12. Brink, A., Moolman, J., da Silva, M.C., et al. 2007. Antimicrobial susceptibility profile of selected bacteraemic pathogens from private institutions in South Africa. S Afr Med J 97: 273–279.PubMedGoogle Scholar
  13. Denno, D.M., Frimpong, E., Gregory, M., Steele, R.W. 2002. Nasopharyngeal carriage and susceptibility patterns of Streptococcus pneumoniae in Kumasi, Ghana. West Afr J Med 21: 233–236.PubMedGoogle Scholar
  14. Feikin, D.R., Davis, M., Nwanyanwu, O.C. et al. 2003. Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children. Pediatr Infect Dis J 22: 564–567.CrossRefPubMedGoogle Scholar
  15. Felmingham, D., White, A.R., Jacobs, M.R. et al. 2005. The Alexander Project: the benefits from a decade of surveillance. J Antimicrob Chemother 56 Suppl 2: ii3–ii21.CrossRefGoogle Scholar
  16. Frost, J.A., Rowe, B., Vandepitte, J. 1982. Acquisition of trimethoprim resistance in epidemic strains of Shigella dysenteriae type 1 from Zaire. Lancet 8278: 963.CrossRefGoogle Scholar
  17. Guévart, E., Solle, J., Mouangue, A. et al. 2006. Antibiotic susceptibility of Vibrio cholerae 01: evolution after prolonged curative and preventive use during the 2004 cholera epidemics in Douala (Cameroon). Med Mal Infect 36: 329–334.CrossRefPubMedGoogle Scholar
  18. Hill, P.C., Akisanya, A., Sankareh, K. et al. 2006. Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian villagers. Clin Infect Dis 43: 673–769.CrossRefPubMedGoogle Scholar
  19. Hirakata, Y., Matsuda, J., Miyazaki, Y. et al. 2005. Regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the Asia-Pacific region (SENTRY 1998–2002). Diagn Microbiol Infect Dis 52: 323–329.CrossRefPubMedGoogle Scholar
  20. Hsu, L.Y., Tan, T.Y., Jureen, R. et al. 2007. Antimicrobial drug resistance in Singapore hospitals. Emerg Infect Dis 13: 1944–1947.PubMedGoogle Scholar
  21. Huebner, R.E., Wasas, A.D., Klugman, K.P. 2000. Trends in antimicrobial resistance and serotype distribution of blood and cerebrospinal fluid isolates of Streptococcus pneumoniae in South Africa, 1991–1998. Int J Infect Dis 4: 214–218.CrossRefPubMedGoogle Scholar
  22. Kacou-N’douba, A., Guessennd-Kouadio, N., Kouassi-M'bengue, A., Dosso, M. 2004. Evolution of Streptococcus pneumoniae antibiotic resistance in Abidjan: update on nasopharyngeal carriage, from 1997 to 2001 Med Mal Infect 34: 83–85.CrossRefPubMedGoogle Scholar
  23. Kariuki, S., Cheesbrough, J., Mavridis, A.K., Hart, C.A. 1999. Typing of salmonella enterica serotype paratyphi C isolates from various countries by plasmid profiles and pulsed-field gel electrophoresis. J Clin Microbiol 37: 2058–2060.PubMedGoogle Scholar
  24. Kariuki, S., Revathi, G., Kariuki, N. et al. 2005. Increasing prevalence of multidrug-resistant non-typhoidal salmonellae, Kenya, 1994–2003. Int J Antimicrob Agents 25: 38–43.CrossRefPubMedGoogle Scholar
  25. Kariuki, S., Revathi, G., Kiiru, J., Lowe, B., Berkley, J.A., Hart, C.A. 2006. Decreasing prevalence of antimicrobial resistance in non-typhoidal Salmonella isolated from children with bacteraemia in a rural district hospital, Kenya. Int J Antimicrob Agents 28:166–171.CrossRefPubMedGoogle Scholar
  26. Kesah, C., Ben Redjeb, S., Odugbemi, T.O. et al. 2003. Prevalence of methicillin-resistant Staphylococcus aureus in eight African hospitals and Malta. Clin Microbiol Infect 9: 153–156.CrossRefPubMedGoogle Scholar
  27. Lamikanra, A., Paul, B.D., Akinwole, O.B., Paul, M.O. 1985. Nasal carriage of Staphylococcus aureus in a population of healthy Nigerian students. J Med Microbiol 19: 211–216.CrossRefPubMedGoogle Scholar
  28. Lee, K., Lim, C.H., Cho, J.H. et al. 2006. High prevalence of ceftazidime-resistant Klebsiella pneumoniae and increase of imipenem-resistant Pseudomonas aeruginosa and Acinetobacter spp. in Korea: a KONSAR program in 2004. Yonsei Med J 47: 634–645.CrossRefPubMedGoogle Scholar
  29. Liebowitz, L.D., Slabbert, M., Huisamen, A. 2003. National surveillance programme on susceptibility patterns of respiratory pathogens in South Africa: moxifloxacin compared with eight other antimicrobial agents. J Clin Pathol 56: 344–347.CrossRefPubMedGoogle Scholar
  30. Malengreau, M., Molima-Kaba, Gillieaux, M., de Feyter, M., Kyele-Duibone, Mukolo-Ndjolo. 1983. Outbreak of Shigella dysentery in eastern Zaire, 1980–1982. Ann Soc Belge Med Trop 63: 59–67.Google Scholar
  31. Mathai, E., Chandy, S., Thomas, K., et al. 2008. Antimicrobial resistance surveillance among commensal Escherichia coli in rural and urban areas in Southern India. Trop Med Int Health13: 41–45.CrossRefPubMedGoogle Scholar
  32. Mehta, A., Rosenthal, V.D., Mehta, Y., et al. 2007. Device-associated nosocomial infection rates in intensive care units of seven Indian cities. Findings of the International Nosocomial Infection Control Consortium (INICC). J Hosp Infect 67: 168–174.PubMedGoogle Scholar
  33. Mukonyora, M., Mabiza, E., Gould, I.M. 1985. Staphylococcal bacteraemia in Zimbabwe 1983. J Infect 10: 233–239.CrossRefPubMedGoogle Scholar
  34. Nkuo-Akenji, T.K., Ntemgwa, M.L., Ndip, R.N. 2001. Asymptomatic salmonellosis and drug susceptibility in the Buea District, Cameroon. Cent Afr J Med 47: 254–257.PubMedGoogle Scholar
  35. Obi, C.L., Makandiramba, B., Robertson, V., Tswana, S.A., Moyo, S.R., Nziramasanga, P. 1998. In-vitro activity of piperacillin and tazobactam combination against clinically significant bacteria. East Afr Med J 75: 162–165.PubMedGoogle Scholar
  36. Ochiai, R.L., Acosta, C.J., Agtini, M. et al. 2007. The use of typhoid vaccines in Asia: the DOMI experience. Clin Infect Dis 45 Suppl 1: S34–S38.CrossRefGoogle Scholar
  37. Ochiai, R.L., Acosta, C.J., Danovaro-Holliday, M.C., et al. 2008. A study of typhoid fever in five Asian countries: disease burden and implications for controls. Bull World Health Organ 86: 260–268.CrossRefPubMedGoogle Scholar
  38. Okeke, I.N., Fayinka, S.T., Lamikanra, A. 2000. Antibiotic resistance in Escherichia coli from Nigerian students, 1986–1998. Emerg Infect Dis. 6: 393–396.CrossRefPubMedGoogle Scholar
  39. Okeke, I.N., Aboderin, O.A., Byarugaba, D.K., Ojo, K.K., Opintan, J.A. 2007. Growing problem of multidrug-resistant enteric pathogens in Africa. Emerg Infect Dis 13: 1640–1646.PubMedGoogle Scholar
  40. Petti, C.A., Polage, C.R., Quinn, T.C., Ronald, A.R., Sande, M.A. 2006. Laboratory medicine in Africa: a barrier to effective health care. Clin Infect Dis 42: 377–382.CrossRefPubMedGoogle Scholar
  41. Seydi, M., Sow, A.I., Soumare, M. et al. 2004. Staphylococcus aureus bacteremia in the Dakar Fann University Hospital. Med Mal Infect 34: 210–215.CrossRefPubMedGoogle Scholar
  42. Shittu, A.O., Lin, J. 2006. Antimicrobial susceptibility patterns and characterization of clinical isolates of Staphylococcus aureus in KwaZulu-Natal province, South Africa. BMC Infect Dis 6: 125.CrossRefPubMedGoogle Scholar
  43. Song, J.H., Sung, S.I., Ko, K.S. et al. 2004. High prevalence of antimicrobial resistance among clinical Streptococcus pneumoniae isolates in Asia (an ANSORP study). Antimicrob Agents Chemother 48: 2101–2107.CrossRefPubMedGoogle Scholar
  44. Srikantiah, P., Girgis, F.Y., Luby, S.P., et al. 2006. Population-based surveillance of typhoid fever in Egypt. Am J Trop Med Hyg 74: 114–119.PubMedGoogle Scholar
  45. Stelling, J.M., O’Brien, T.F. 1997. Surveillance of antimicrobial resistance: the WHONET program. Clin Infect Dis 24 Suppl 1: S157–S168.Google Scholar
  46. Urassa, W.K., Mhando, Y.B., Mhalu, F.S., Mjaonga, S.J. 2000. Antimicrobial susceptibility pattern of Vibrio cholerae O1 strains during two cholera outbreaks in Dar es Salaam, Tanzania. East Afr Med J 77: 350–353.PubMedGoogle Scholar
  47. Van den Ende, J. 2007. Antibiotic resistance in hospitals – are surveillance data of any value? S Afr Med J 2007 97: 264–266.Google Scholar
  48. Vaughan, J.P., Walt, G. 1984. Implementing primary health care: some problems of creating national programmes. Trop Doct 14: 108–113.PubMedGoogle Scholar
  49. Von Seidlein, L., Kim, D.R., Ali, M. et al. 2006. A multicentre study of Shigella diarrhoea in six Asian countries: disease burden, clinical manifestations, and microbiology. PLoS Med 3: e353.CrossRefGoogle Scholar
  50. WHO Global Strategy for Containment of Antimicrobial Resistance. WHO/CDS/CSR/DRS/2001.2.Google Scholar
  51. Zinn, C.S., Westh, H., Rosdahl, V.T. et al. 2004. An international multicenter study of antimicrobial resistance and typing of hospital Staphylococcus aureus isolates from 21 laboratories in 19 countries or states. Microb Drug Resist 10: 160–168.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Clinical SciencesInstitute of Tropical MedicineAntwerpBelgium
  2. 2.Department of Medical MicrobiologyAberdeen Royal InfirmaryForesterhillScotland

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