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Prevalence of Resistant Enterococci in Developing Countries

  • Lorena Abadía-Patiño
Chapter

Abstract

Glycopeptide resistance in enterococci is a problem of worldwide distribution, with a wider incidence in industrialized countries. This incidence is reflected as both nosocomial illnesses in the United States, because of the extensive use of antibiotic therapy, and community-borne diseases in Europe, due to the use of avoparcin as a growth promoter in animal husbandry. Vancomycin-resistant strains, however, have started to emerge in the developing world, where VRE carriers in the hospital may infect themselves upon receiving either third-generation cephalosporins to combat Gram-negative infections or vancomycin, for the treatment of severe methicillin-resistant Staphylococcus infections. Detecting VRE carriers is then of paramount importance, and although several techniques for that purpose do exist, no gold standard has been proposed to certify the accuracy or sensitivity of the assays, and it all depends on the inoculum in the intestine.

Keywords

Rectal Swab Prevalence Index Chicken Sample Glycopeptide Resistance Polish Hospital 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Afkhamzadehm, A. 2004. Risk factors of vancomycin-resistant enterococci colonization in patients admitted in Namazi hospital-Shiraz 2004. Shiraz: Shiraz University of Medical Sciences.Google Scholar
  2. Almeida, R. T., Filho, M., Silveira, R., Rodrigues, C. A. N., Filho, I. P., Nascimento, J. E., Ferreira, R. S., Moraes, II R. F., Boelens, L. M. P., Belkum, H., Felipe, A. V. 2004. Molecular epidemiology and antimicrobial susceptibility of enterococci from Brazilian Intensive Care Units. Braz. J. Infect. Dis. 8:197–205.Google Scholar
  3. Arias, C. A, Reyes, J., Zúñiga, M., Cortés, L., Cruz, C., Rico C. L., and D. Panesso on behalf of the Colombian Antimicrobial Resistance Group (RESCOL). 2003. Multicentre surveillance of antimicrobial resistance in enterococci and staphylococci from Colombian hospitals, 2001–2002. J. Antimicrob. Chemother. 51:59–68.Google Scholar
  4. Arthur, M., Reynolds, R., and Courvalin, P. 1996. Glycopeptide resistance in enterococci. Trends Microbiol. 4:401–407.PubMedCrossRefGoogle Scholar
  5. Assadian, O., Askarian, M., Stadler, M., and Shaghaghian, S. 2007. Prevalence of vancomycin-resistant enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran. BMC Infect. Dis. 7:52–56.PubMedCrossRefGoogle Scholar
  6. Aznar, E., Buendía, B., Garcia-Peñuela, E., Escudero, E., Alarcon, T., and Lopez-Brea, M. 2004. Community-acquired urinary tract infection caused by vancomycin-resistant Enterococcus faecalis clinical isolate. Rev. Esp. Quimioter. 17:263–265.PubMedGoogle Scholar
  7. Basustaoglu, A., Aydogan, H., Beyan, C., Yalcin, A., and Unal, S. 2001. First glycopeptide-resistant Enterococcus faecium isolate from blood culture in Ankara, Turkey. Emerg. Infect. Dis. 7:160–161.PubMedCrossRefGoogle Scholar
  8. Bazet, C., Blanco, J., Seija, V., and Palacio, R. 2005. Enterococos resistentes a vancomicina. Un problema emergente en Uruguay. Rev. Med. Uruguay 21:151–158.Google Scholar
  9. Bergerova, T., and Turkova, S. 1997. First finding of vancomycin-resistant enterococci in the Faculty Hospital, Plzen˘. Klin. Mikrobiol. Inf. Lek. 3:287–288.Google Scholar
  10. Bilikova, E., Hanzen, J., Roidova, A., Trupl, J., Lamosova, J., Liskova, A., Macekova, J., Szvenyova, Z., Svetlansky, I., and Krcméry, V. 2001. Bacteremia due to vancomycin resistant enterococci in Slovakia. J. Antimicrob. Chemother. 47:362–364.PubMedCrossRefGoogle Scholar
  11. Boyce, J. M., Opal, S. M., Chow, J. W., Zervos, M. J., Potter-Bynoe, G., Sherman, C. B., Romulo, R. L. C., Fortna, S., and Medeiros, A. A. 1994. Outbreak of multidrug-resistant Enterococcus faecium with transferable vanB class vancomycin resistance. J. Clin. Microbiol. 32:1148–1153.PubMedGoogle Scholar
  12. Budavari, S. M., Saunders, G. L., Liebowitz, L. D., Khoosal, M., and Crewe-Brown, H. H. 1997. Emergence of vancomycin-resistant enterococci in South Africa. S. Afr. Med. J. 87:1557.PubMedGoogle Scholar
  13. Butaye, P., Devriese, L. A., Goosens, H., Leven, M., and Haesebrousk, F. 1999. Enterococci with acquired vancomycin resistance in pigs and chickens of different age groups. Antimicrob. Agents Chemother. 43:365–366.PubMedGoogle Scholar
  14. Calderón-Jaimes, E., Arredondo-García, J. L., Aguilar-Ituarte, F., and García-Roca, P. 2003. In vitro antimicrobial susceptibility in clinical isolates of Enterococcus species. Salud Pública de México. 45(2):96–101.PubMedCrossRefGoogle Scholar
  15. Camargo, I. L. B. C., Barth, A. L., Pilger, K., Seligman, B.G.S., Machado, A.R.L., and Darini, A.L.C. 2004a. Enterococcus gallinarum carrying the vanA gene cluster: first report in Brazil. Braz. J. Med. Biol. Res. 37:1669–1671.Google Scholar
  16. Camargo, I. L. B. C., Del Peloso, P., Da Costa, L. F., Goldman, G. H., and Darini, A. L. C. 2004b. Identification of an unusual vanA element in glycopeptide-resistant Enterococcus faecium in Brazil following international transfer of a bone marrow transplant patient. Can. J. Microbiol. 50:767–770.Google Scholar
  17. Casellas, J. M., Tome, G., Goldberg, M., Gilardoni, M., Rolon, M. J., Lopez-Furst, M. J., Marcopido, M. 1996. Primer aislamiento en Argentina de Enterococcus faecalis resistente a vancomicina. La faceta del Cindim. 4:22.Google Scholar
  18. Cereda, R. F., Sader, H. S., Jones, R. N., Sejas, L., Machado, A. M., Zanatta, Y. P., Rego, S. T. M. S., Medeiros, E. A. S. 2001. Enterococcus faecalis resistant to vancomycin and teicoplanin (VanA phenotype) isolated from a bone narrow transplanted patient in Brazil. Braz. J. Infect. Dis. 5:40–46.PubMedCrossRefGoogle Scholar
  19. Cereda, R. F., Gales, A. C., Silbert, S., Jones, R. N., and Sader, H. S. 2002. Molecular typing and antimicrobial susceptibility of vancomycin resistant Enterococcus faecium in Brazil. Infect. Contr. Hosp. Epidemiol. 23:19–22.CrossRefGoogle Scholar
  20. Cetinkaya, Y., Falk, P., and Mayhall, C. G. 2000. Vancomycin-resistant enterococci. Clin. Microbiol. Rev. 13:686–707.PubMedCrossRefGoogle Scholar
  21. Cheng, A. F., Char, T. S., and Ling, J. M. 2002. Are multiply resistant enterococci a common phenomenon in Hong Kong? J. Antimicrob. Chemother. 50:761–763.PubMedCrossRefGoogle Scholar
  22. Colak, D., Nass, T., Gunseren, F., Fortineau, N., Ogunc, D., Gultekin, M., and Nordmann, P. 2002. First outbreak of vancomycin-resistant enterococci in a tertiary hospital in Turkey. J. Antimicrob. Chemother. 50:397–401.PubMedCrossRefGoogle Scholar
  23. Coleri, A., Cokmus, C., Ozcan, B., Akcelik, M., and Tukel, C. 2004. Determination of antibiotic resistance and resistance plasmids of clinical Enterococcus species. J. Gen. Appl. Microbiol. 50:213–219.PubMedCrossRefGoogle Scholar
  24. Coque, T. M., Tomayko, J. F., Ricke, S. C., Okhyusen, P. C., and Murray, B. E. 1996. Vancomycin-resistant enterococci from nosocomial, community and animal sources in the United States. Antimicrob. Agents Chemother. 40:2605–2609.PubMedGoogle Scholar
  25. Cornejo-Juarez, P., Velásquez-Acosta, C., Díaz-Gonzalez, A., and Volkow-Fernandez P. 2005. Tendencia del perfil de sensibilidad antimicrobiana de los aislamientos de sangre en un hospital oncológico (1998–2003). Salud Pública Mex. 47:288–293.PubMedGoogle Scholar
  26. Corso, A., Faccone, D., Gagetti, P., Togneri, A., Lopardo, H., Melano, R., Rodríguez, V., Rodriguez, M., and Galas, M. 2005. First report of VanA Enterococcus gallinarum dissemination within an intensive care unit in Argentina. Inter. J. Antimicrob. Agents 25:51–56.CrossRefGoogle Scholar
  27. Cuellar-Rodríguez, J., Galindo-Fraga, A., Guevara, V., Pérez-Jiménez, C., Espinosa-Aguilar, L., Rolón, A. L., Hernández-Cruz, A., López-Jácome, E., Bobadilla-del-Valle, M., Martínez-Gamboa, A., Ponce-de-León, A., and Sifuentes-Osornio, J. 2007. Vancomycin resistant enterococci, Mexico City. Emerg. Infect. Dis. 13(5):798–799.PubMedGoogle Scholar
  28. Dalla Costa, L. M., Souza, D. C., Martins, L. T. F., Zanella, R. C., Brandileone, M. C., Bokermann, S., Sader, H. S., and Souza, H. A. P. H. M. 1998. Vancomycin-resistant Enterococcus faecium: first case in Brazil. Braz. J. Infect. Dis. 2:160–2163.PubMedGoogle Scholar
  29. Dalla Costa, L. M., Reynolds, P. E., Souza, H. A. P. H. M., Souza, D. C., Palepou, M. F. I., and Woodford, N. 2000. Characterization of a divergent VanD-type resistance element from the first glycopeptide-resistant strain of Enterococcus faecium isolated in Brazil. Antimicrob. Agents Chemother. 44:3444–3446.PubMedCrossRefGoogle Scholar
  30. Dekhnich, A., Edelstain, I., Narezkina, A., and Stratchounski, L. 2001. Antimicrobial resistance of nosocomial strains of Enterococcus spp. in Russia. Poster Nr. P 1207. http://www.antibiotic.ru/files/pdf/en/eccmid_arnsesru.pdf
  31. Derby, P., Allan, B., Lambrick, M., and Gay-Elisha, B. 1998. Detection of glycopeptide-resistant enterococci using susceptibility testing and PCR. S. Afr. J. Epidemiol. Infect. 13:66–69.Google Scholar
  32. Emaneini, M., Farhad, B., Hashemi, M. A., Aligholi, M., and Fatholahzadeh, B. 2005. Detection of vanB genotype enterococci in Iran. Inter. J. Antimicrob. Agents 26:95–99.CrossRefGoogle Scholar
  33. Endtz, H. P., van den Braak, N., van Belkum, A. Kluytmans, J. A., Koeleman, J. G., Spanjaard, L., Voss, A., Weersink, A. J., Vandenbroucke-Grauls, C. M., Buiting, A. G., van Duin, A., and Verbrugh, H. A. 1997. Fecal carriage of vancomycin-resistant enterococci in hospitalized patients and those living in the community in the Netherlands. J. Clin. Microbiol. 35:3026–3031.PubMedGoogle Scholar
  34. Esmaeli, H., Holz, E. R., Ahmadi, M. A., Kathren, R. A., and Raad, I. I. 2003. Endogenous endophtalmitis secondary a vancomycin-resistant enterococci infection. Retina 23:118–119.PubMedCrossRefGoogle Scholar
  35. Fatholahzadeh, B., Hashemi, F. B., Emaneini, M., Aligholi, M., Nakhjavani, F. A., Kazemi, B., 2006. Detection of vancomycin resistant enterococci (VRE) isolated from urinary tract infections (UTI) in Tehran, Iran. DARU. 14(3):141–146.Google Scholar
  36. Feizabadi, M. M., Asadi, S., Aliahmadi, A., Parvin, M., Parastan, R., Shayegh, M., and Etemadi, G. 2004. Drug resistant patterns of enterococci recovered from patients in Tehran during 2000–2003. Int. J. Antimicrob. Agents 24:521–522.CrossRefGoogle Scholar
  37. Fujita, N., Yoshimura, M., Komori, T., Tanimoto, K., and Ike, Y. 1998. First report of the isolation of high-level vancomycin-resistant Enterococcus faecium from a patient in Japan. Antimicrob. Agents Chemother. 42:2150.PubMedGoogle Scholar
  38. Furtado, G. H. C., Martins, S. T., Coutinho, A. P., Wey, S. B, and Medeiros, E. A S. 2005. Prevalence and factors associated with rectal vancomycin-resistant enterococci colonization in two intensive care units in São Paulo, Brazil. Braz. J. Infect. Dis. 9:64–69.PubMedCrossRefGoogle Scholar
  39. Giglio, M. S., Farías, O., Lafourcade, M., and Pinto, M. E. 1999. Vigilancia de susceptibilidad de cocáceas grampositivas a betalactámicos, glicopéptidos y otros antimicrobianos. Rev. Med. Chil. 127:8.Google Scholar
  40. Han, D. P., Wisniewski, S. R., and Wilson, A. 1996. Spectrum and susceptibilities of microbiologic isolates of endophthalmitis vitrectomy study. Am. J. Ophthalmol. 122:1–17.PubMedGoogle Scholar
  41. Hawkey, P. M. 1986. Resistant bacteria in the normal human flora. J. Antimicrob. Chemother. 18(Suppl. C):133–139.PubMedGoogle Scholar
  42. Hryniewicz, W., Zaręba, T., and Kawalec, M. 1998. Susceptibility patterns of Enterococcus spp. isolated in Poland during 1996. Int. J. Antimicrob. Agents 10:303–307.CrossRefGoogle Scholar
  43. Hryniewicz, W., Szczypa, K., Bronk, M. Samet, A., Hellmann, A., and Trzciński, K. 1999a. First report of vancomycin-resistant Enterococcus faecium isolated in Poland. Clin. Microbiol. Infect. 5:503–505.Google Scholar
  44. Hryniewicz, W. 1999b. Antibiotic resistant in Central Europe. Abstract on the 9th ECCMID, Berlin. Clin. Microbiol. Infect. 8(Suppl. 1):234.Google Scholar
  45. Hsueh, P. R., Chen, W. H., Teng, L. J., and Luh. K. T. 2005. Nosocomial infections due to methicillin-resistant S. aureus and vancomycin-resistant enterococci at a university hospital in Taiwan from 1991 to 2003: resistant trends, antibiotics usage and in vitro activities of newer antimicrobial agents. Int. J. Antimicrob. Agents 26:43–49.PubMedCrossRefGoogle Scholar
  46. Kawalec, M., Gniadkowski, M., Kedzierska, Skotnicki, J. A., Fiett, J., and Hryniewicz, W. 2001. Selection of a teicoplanin-resistant Enterococcus faecium mutant during an outbreak caused by vancomycin-resistant enterococci with the VanB phenotype. J. Clin. Microbiol. 39:4274–4282.PubMedCrossRefGoogle Scholar
  47. Kawalec, M., Ziółkowski, R., Ozorowski, T., Kędzierska, J., Baran, M., and Hryniewicz, W. 2004. 14th European Congress Clinical Microbiology Infectious Diseases. Abstract P812. Clin. Microbiol. Infect. 10(Suppl.3):207.Google Scholar
  48. Kawalec, M., Pietras, Z., Daniłowicz, E., Jakubczak, A., Gniadkowski, M., Hryniewicz, W., and Willems, R. J. L. 2007. Clonal structure of Enterococcus faecalis isolated from Polish hospitals: characterization of epidemic clones. J. Clin. Micrbiol. 45(1):147–153.CrossRefGoogle Scholar
  49. Kim, J. M., and Song, Y. G. 1998. Vancomycin-resistant enterococcal infections in Korea. Yonsei Med. J. 39:562–568.PubMedGoogle Scholar
  50. Kholy, A. E., Baseem, H., Hall, G. S., Procop, G. W., and Longworth, D. L. 2002. Antimicrobial resistance in Cairo, Egypt 1999–2000: a survey of five hospitals. J. Antimicrob. Chemother. 51:625–630.CrossRefGoogle Scholar
  51. Knudtson, L. M., and Hartman, P. A. 1993. Antibiotic resistance among enterococcal isolates from environmental and clinical sources. J. Food Protect. 56:489–492.Google Scholar
  52. Kolař, M., Vagnerova, I., Latal, T., Urbanek, K., Typovska, H., Hubacek, J., Papajik, T., Raida, L., and Faber, E. 2002. The occurrence of vancomycin-resistant enterococci in hematological patients in relation to antibiotic use. Microbiologica 25:205–212.PubMedGoogle Scholar
  53. Kolař, M., Čekanova, L., Vagnerova, I., Kesselova, M., Sauer, P., Koukalova, D., and Hejnar, P. 2004. Molecular-biological analysis of vancomycin-resistant enterococci isolated from a community in the Czech Republic. Biomed. Papers 148(2):167–169.Google Scholar
  54. Kollar, M. 1999. Susceptibility of enterococci to vancomycin. Report from a University Hospital hematology ward. Clin. Microbiol. 5:13–17.Google Scholar
  55. Krcméry, V. Jr., Hryiewicz, W., Ludwig, E., Radzilowski, H., Stratchoynski, C., Navachin, S. M.1998. Epidemiology of antimicrobial resistant in Central/Eastern Europe. J. Pub. Health. 1:13–30.Google Scholar
  56. Lauderdale, T. L., McDonald, L. C., Shiau, Y. R., Chen, P.-C., Wang, H.-Y., Lai, J.-F., and Ho, M. 2002. Vancomycin-resistant enterococci from humans and retail chickens in Taiwan with unique phenotype VanB-vanA genotype incongruence. Antimicrob. Agents Chemother. 46:525–527.PubMedCrossRefGoogle Scholar
  57. Leme, I. L., Piantino, A. J., Bottino, J. A., and Pignatari, A. C. 2000. Glycopeptides susceptibility among enterococci isolated from a poultry farm in São Paulo, Brazil (1996/1997). Braz. J. Microbiol. 31:53–57.Google Scholar
  58. Llittvik, A. M., López, T. N., González, S. E., Fernández, C. M., and Pavan, J. V. 2006. Colonization with vancomycin-resistant enterococci (VRE) in intensive care unit patients in Cordoba City, Argentina. Rev. Argent. Microbiol. 38:28–30.Google Scholar
  59. Low, D. E., Keller, N., Barth, A., and Jones, R. N. 2001. Clinical prevalence, antimicrobial susceptibility, and geographic resistance patterns of enterococci: results from the SENTRY Antimicrobial Surveillance Program, 1997–1999. Clin. Infect. Dis. 32(Suppl.2):S133–S145.Google Scholar
  60. Marin, M. E., Mera, J. R., Arduino, R. C., Correa, A. P., Coque, T. M., Stamboulian, D., and Murray, B. E. 1998. First report of vancomycin-resistant Enterococcus faecium isolated in Argentina. Clin. Infect. Dis. 26:235–236.PubMedCrossRefGoogle Scholar
  61. McDonald, L. C., Garza, L. R., and Jarvis, W. R. 1999. Proficiency of clinical laboratories in and near Monterrey, Mexico, to detect vancomycin-resistant enterococci. Emerg. Infect. Dis. 5:143–146.PubMedCrossRefGoogle Scholar
  62. McNeeley, D. F., Brown, A. E., Noel, G. J., Chung, M., and de Lancastre, H. 1998. An investigation of vancomycin-resistant Enterococcus faecium within the pediatric service of a large urban medical center. Pediatr. Infect. Dis. J. 17:184–188.PubMedCrossRefGoogle Scholar
  63. Miranda, G., Lee, L., Kelly, C., Solórzano, F., Solórzano, F., Leaños, B., Muñoz, O., and Patterson, J. E. 2001. Antimicrobial resistance from enterococci in a pediatric hospital. Plasmids in Enterococcus faecalis isolates with high-level gentamicin and streptomycin resistance. Arch. Med. Res. 32:159–163.PubMedCrossRefGoogle Scholar
  64. Miranda, G., Corso, A., Melano, R., Arismendi, P., Rodríguez, M., and Garbervetsky, L. 2003. First isolation of vancomycin-resistant Enterococcus faecium with vanB genotype in Argentina: presentation of two cases. Rev. Argent. Microbiol. 35(1):41–44.Google Scholar
  65. Mironova, A., Cherkashin, E., Kliasova, G., Tishkov, V., Brilliantova, A., Rezvan, S., and Sidorenko, S. 2006. First detection of vancomycin-resistant enterococci in Russia: genetic background. 16th European Congress of Clinical of Clinical Microbiology and Infectious Diseases. Nice. France. Abstract 1819.Google Scholar
  66. Montilla, N., León, Y., Payares, D., Paraqueimo, M., Machado, Y., Ojeda, X., Marcano, D., and Vacampenhaud, M. 2007. Enterococcus faecium resistente a vancomicina con genotipo vanA en el hospital Dr. Domingo Luciani. Caracas, Venezuela. Abstract 06. XVI Jornadas Nacionales de Infectología. XIII Jornadas Nororientales de Infectología. Margarita, Estado Nueva Esparta, Venezuela. Bol. Venez. Infectol. 18(2):53.Google Scholar
  67. Morfín, O. R., Heredia, C. J., Pinto, T. D., Rodríguez, C. J. J, and Rodríguez, E. 1992. E. faecalis and E. faecium resistance patterns, México. Abstract C-260. En programa y abstractos de la 92a American Society of Microbiology General Meeting. 464.Google Scholar
  68. Morfín, R., Esparza, S., Atilano, G., Pinto, D., Heredia, J., Rodríguez, J. J., and Rodríguez, E. 1999. Tendencias de resistencia en enterococos: 1991–1999. Enf. Infec. Microbial. 19(5):222–226.Google Scholar
  69. Murray, B. E., Singh, K. V., Heath, J. D., Sharma, B. R., and Weinstock, G. M. 1990. Comparison of genomic DNAs of different enterococcal isolates using restriction endonucleases with infrequent recognition sites. J. Clin. Microbiol. 28:2059–2063.PubMedGoogle Scholar
  70. Nodarse, R. 2005. Informe Corto. Rev. Cub. Med. Mil. 51:63–67.Google Scholar
  71. Novicki, T. J., Schapiro, J. M., Ulness, B. K., Sebeste, A., Busse-Johnston, L., Swanson, K. M., Swanzy, S. R., Leisenring, W., and Limaye, A. P. 2004. Convenient selective differential broth for isolation of vancomycin-resistant Enterococcus from fecal material. J. Clin. Microbiol. 42:1637–1640.PubMedCrossRefGoogle Scholar
  72. Oncu, S., Punar, M., and Eraksoy, H. 2004. Susceptibility patterns of enterococci causing infections. Tohoku J. Exp. Med. 202:23–29.PubMedCrossRefGoogle Scholar
  73. Palazzo, I. C. V., Camargo, I. B. C., Zanella, R. C., and Darini, A. L. C. 2006. Evaluation of clonality on enterococci isolated in Brazil carrying Tn1546–like elements associated to vanA plasmids FEMS Microbiol. Lett. 258:29–36.Google Scholar
  74. Panesso, D., Ospina, S., Robledo, J., Vela, M. C., Peña, J., Hernández, O., Reyes, J., and Arias, C. A. 2002. First characterization of a cluster of VanA-type glycopeptide resistant Enterococcus faecium, Colombia. Emerg. Infect. Dis. 8(9):961–965.PubMedGoogle Scholar
  75. Paredes, F., and Hernán, W. 2007. Características clínico-epidemiológicas de 14 casos con aislamiento clínico de enterococo resistente a vancomicina en el Hospital Nacional Edgardo Rebagliati Martins. Rev. Med. Hered. 18(2):68–75.Google Scholar
  76. Park, I. J., Lee, W. G., Lim, Y. A., and Cho, S. R. 2007. Genetic rearrangements of Tn1546–like elements in vancomycin-resistant Enterococcus faecium isolates collected from hospitalized patients over a seven-year period. J. Clin. Microbiol. 45(2):3903–3908.PubMedCrossRefGoogle Scholar
  77. Perdomo, Y., Borrero, L., González, S., Castillo, Z., Castillo, O., and Sánchez, C. 2006. Enterococcus faecium resistente a vancomicina, genotipo vanA, en la ciudad de valencia. Reporte del primer caso. Abstract 141. VII Congreso Venezolano de Infectología Dr. Belisario Gallegos. XIV Jornadas Guayanesas de Infectología. Puerto Ordaz. Estado Bolívar. Venezuela.Google Scholar
  78. Pineda, M., Perozo-Mena, A., Lleras, A., Bonilla, X., Mendez, A., González, M., and Villalobos, H., 2007. Primer reporte de Enterococcus resistente a vancomicina en el estado Zulia. Abstract BA-16. XXXI Jornadas Venezolanas de Microbiología. “Dr. Sócrates Medina y Elba Aracelis Padrón. Ciudad Bolívar, Estado Bolívar. Venezuela.Google Scholar
  79. Prakash, V. P., Rao, S. R., and Parija, S. C. 2005. Emergence of unusual species of enterococci causing infections, South India. BMC Infect. Dis. 5:14.PubMedCrossRefGoogle Scholar
  80. Quiñones, D. 2002. Fenotipos de resistencia antimicrobiana y genes de resistencia en Enterococcus sp de importancia clínica en Cuba. Rev. Latinoam. Microbiol. 44(4):150.Google Scholar
  81. Quiñones, D., Goñib, P., Rubioc, M., Duranc, E., and Gómez-Lusb, R. 2005. Enterococci spp. isolated from Cuba: species frequency of occurrence and antimicrobial susceptibility profile. Diagn. Microbiol. Infect. Dis. 51(1):63–67.PubMedCrossRefGoogle Scholar
  82. Radu, S., Toosa, H., Rahim, R. A., Reezal, A., Ahmad, M., Hamid, A. N., Rusul, G., and Nishibuchid, M. 2001. Occurrence of the vanA and vanC2/C3 genes in Enterococcus species isolated from poultry sources in Malaysia. Diagn. Microbiol. Infect. Dis. 39:145–153.PubMedCrossRefGoogle Scholar
  83. Raja, N. S., Karunakaran, R., Ngeow, Y. F., and Awang, R. 2005. Community-acquired vancomycin-resistant Enterococcus faecium: a case report from Malaysia. J. Med. Microbiol. 54:901–903.PubMedCrossRefGoogle Scholar
  84. Reis, A. O., Cordeiro, J. C., Machado, A. M., and Sader, H. S. 2001. In vitro antimicrobial activity against vancomycin-resistant enterococci isolated in Brazilian hospitals. Braz. J. Infect. Dis. 5:243–251.PubMedCrossRefGoogle Scholar
  85. Ruiz, N., Vásquez, Y., Gayoso, E., Moy, F., Guzmán, M., Hernández, M., and Spadola, E. 2007. Enterococcus faecium resistente a vancomicina. Reporte del primer caso en el hospital militar “Dr. C. Arvelo” y revisión de la literatura. Abstract 07. XVI Jornadas Nacionales de Infectología. XIII Jornadas Nororientales de Infectología. Margarita, Estado Nueva Esparta, Venezuela. Bol. Venez. Infectol. 18(2):53.Google Scholar
  86. Ruiz-Garbajosa, P., Bonten, M. J., Robinson, D. A., Top, J., Nallapareddy, S. R., Torres, C., Coque, T. M., Canton, R., Baquero, F., Murray, B. E., Del Campo, R., and Willems, R. J. 2006. Multilocus sequence typing scheme for Enterococcus faecalis reveals hospital-adapted genetic complexes in a background of high rates of recombination. J. Clin. Microbiol. 44:2220–2228.PubMedCrossRefGoogle Scholar
  87. Ruoff, K. L., de la Maza, L., Murtagh, M. J., Spargo, J. D., and Ferraro, M. J. 1990. Species identities of enterococci isolated from clinical specimens. J. Clin. Microbiol. 28:435–443.PubMedGoogle Scholar
  88. Samet, A., Bronk, M., Hellmann, A., and Kur, J. 1999. Isolation and epidemiological study of vancomycin-resistant Enterococcus faecium from patients of a haematological unit in Poland. J. Hosp. Infect. 41:137–143.PubMedCrossRefGoogle Scholar
  89. Scott, I. U., Loo, R. H., Flynn, H. W. Jr., and Miller, W. 2003. Endophtalmitis caused by Enterococcus faecalis: antibiotic selection and treatment outcomes. Opthalmol. 110:1573–1577.CrossRefGoogle Scholar
  90. Shin, J. W., Yong, D., and Kim, M. S. 2003. Sudden increase of vancomycin-resistant enterococcal infections in a Korean tertiary care hospital: possible consequences of increased use of oral vancomycin. J. Infect. Chemother. 9:62–67.PubMedCrossRefGoogle Scholar
  91. Sifuentes-Osornio, J., Ponce-de-León, A., Muñoz-Trejo, T., Villalobos-Zapata, Y., Ontiveros-Rodriguez, C., and Gómez-Roldan, C. 1996. Antimicrobial susceptibility patterns and high-level gentamicin resistance among enterococci isolated in a Mexican tertiary care center. Rev. Invest. Clin. 48:91–96.PubMedGoogle Scholar
  92. Silva, M., Pitteloud, J., Villarroel, E., Figueredo, A., Payares, D., Sánchez, D., Martín, A., Carvajal, A., López, L., Villarroel, E., Khalil, R., Núñez, M., González, E., Pacheco, C., and Sojo, G. 2007. Aislamiento de Enterococcus faecium resistente a vancomicina: características clínicas y epidemiológicas de los pacientes. Hospital Universitario de Caracas. 2005–2007. Abstract 46. XVI Jornadas Nacionales de Infectología. XIII Jornadas Nororientales de Infectología. Margarita, Estado Nueva Esparta, Venezuela. Bol. Venez. Infectol. 18(2):72.Google Scholar
  93. Stošovic, B., Stepanovic, S., Donabedian, S., Tošic, T., and Jovanovic, M. 2004. Vancomycin resistant Enterococcus faecalis in Serbia. Emerg. Infect. Dis. 10(1):157–158.PubMedGoogle Scholar
  94. Taneja, N., Rani, P., Emmanuel, R., and Sharma, M. 2004. Significance of vancomycin resistant enterococci from urinary specimens at a tertiary care centre in northern India. Indian J. Med. Res. 119:72–74.PubMedGoogle Scholar
  95. Tang, C. W., Cheng, C. K., and Lee, T. S. 2007. Comunity-adquired bled-related endophtalmitis caused by vancomycin-resistant enterococci. Can. J. Opthalmol. 42:477–478.CrossRefGoogle Scholar
  96. Targa, L., Carbone, E., and Gallego, V. 1997. Brote epidémico por Enterococcus faecium resistente a la vancomicina en un hospital de Buenos Aires. I Congreso Internacional de Infectología y Microbiología Clínica SADI-SADEBAC, Resumen H330, Buenos Aires, Argentina.Google Scholar
  97. Tenover, F. C. 1998. Laboratory methods of surveillance of vancomycin-resistant enterococci. Clin. Microbiol. News Lett. 20:1–5.CrossRefGoogle Scholar
  98. Thal, L.A., Chow, J. W., Mahayani, R., H. Bonilla, H., Perri, M. B., Donabedian, S. A., Silverman, J., Taber, S., and Zervos, M. J. 1995. Characterisation of antimicrobial resistance in enterococci of animal origin. Antimicrob. Agents Chemother. 39:2112–2115.Google Scholar
  99. Toosa, H., Son, R., Rasul, G., Reezal, A., Rahim, R., Ahmad, N., and Ling, O. 2001. Detection of vancomycin resistant Enterococcus spp (VRE) from poultry. Malays. J. Med. Sci. 8(1):53–58.Google Scholar
  100. Udo, E. E., Al-Sweih, N., and Chugh, T. D. 2002. Antibiotic resistance of enterococci isolated at a teaching hospital in Kuwait. Diagn. Microbiol. Infect. Dis. 43:233–238.PubMedCrossRefGoogle Scholar
  101. Udo, E. E., Al-Sweih, N, Phillips, O. A., and Chugh, T. D. 2003. Species prevalence and antibacterial resistance of enterococci isolated in Kuwait hospitals. J. Med. Microbiol. 52:163–168.PubMedCrossRefGoogle Scholar
  102. Urbásková, P. 1999. Survey of resistance of enterococcal isolates to antibiotics in Czech Republic. Clin. Microbiol. 6:113–118.Google Scholar
  103. Urumova, V., Lyutzkanov, M., and Petrov, M. 2005. In vitro study of antimicrobial sensitivity of Enterococcus isolates from farm birds. Trakia. J. Sci. 3(5):40–45.Google Scholar
  104. van den Bogaard, A. E., Willems, R., London, N., Top, J., and Stobberingh, E. E. 2002. Antibiotic resistance and faecal enterococci in poultry, poultry farmers and poultry slaughterers. J. Antimicrob. Chemother. 49:497–505.PubMedCrossRefGoogle Scholar
  105. Vásquez, Y., Guzmán, M., Ruiz, N., Gayoso, E., Moy, F., Hernández, M., Spadola, E., and Córdova, J. 2007. Endocarditis por Enterococcus faecalis en paciente trasplantado renal en el Hospital Militar “Dr. Carlos Arvelo” a propósito de un caso. Abstract 47. XVI Jornadas Nacionales de Infectología. XIII Jornadas Nororientales de Infectología. Margarita, Estado Nueva Esparta, Venezuela. Bol. Venez. Infectol. 18(2):72.Google Scholar
  106. Vilela, M. A., de Souza, S. L., Palazzo, I. C. V., Ferreira, J. C., de Morais M. A. Jr, da Costa, A. L., de Morais, M. M. C. 2006. Identification and molecular characterization of VanA-type vancomycin-resistant Enterococcus faecalis in Northeast of Brazil. Mem. Inst. Oswaldo. Cruz. 101(7):716–719.CrossRefGoogle Scholar
  107. von Gottberg, A., van Nierop, W., Dusé, A., Kassel, M., McCarthy, K., Brink, A., Meyers, M., Smego, R., and Koornhof, H. 2000. Epidemiology of glycopeptide-resistant enterococci colonizing high-risk patients in hospitals in Johannesburg, Republic of South Africa. J. Clin. Microbiol. 38(2):905–909.Google Scholar
  108. Woodford, N., Adebiyi, A. M., Palepou, M. F., and Cookson, B. D. 1998. Diversity of VanA glycopeptide resistance elements in enterococci from humans and nonhuman sources. Antimicrob. Agents Chemother. 42:502–508.PubMedGoogle Scholar
  109. Batista Xavier, D., Moreno, F. E., and Titze-de-Almeida, R. 2006. Absence of VanA- and VanB-containing enterococci in poultry raised on non intensive production farms in Brazil. Appl. Environ. Microbiol. 72(4):3072–3073.PubMedCrossRefGoogle Scholar
  110. Yang, J., Lee, D., Kim, Y., Kang, B., Kim, K., and Ha, N. 2007. Occurrence of the van genes in Enterococcus faecalis and Enterococcus faecium from clinical isolates in Korea. Arch. Pharm. Res. 30(3):329–336.PubMedCrossRefGoogle Scholar
  111. Yu, H. S., Seol, S. Y., and Cho, D. T. 2003. Diversity of Tn1546-like elements in vancomycin-resistant enterococci isolated from humans and poultry in Korea. J. Clin. Microbiol. 41:2641–2643.PubMedCrossRefGoogle Scholar
  112. Zanella, R. C., Valdetaro, F., Lovgren, M., Tyrrel, G. J, Bokermann, S, Almeida, S. C. G, Vieira, V. S. D, and Brandileone, M. C. C. 1999. First confirmed case of a vancomycin-resistant Enterococcus faecium with VanA phenotype from Brasil: isolation from a meningitis case in São Paulo. Microbiol. Drug. Resist. 5:159–162.CrossRefGoogle Scholar
  113. Zheng, B., Tomita, H., Xiao, Y. H., Wang, S., Li, Y., and Ike, Y. 2007. Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from Mainland China. J. Clin. Microbiol. 45(9): 2813–2818.PubMedCrossRefGoogle Scholar
  114. Zouain, M. G., and Araj, G. F. 2001. Antimicrobial resistance of enterococci in Lebanon. Int. J. Antimicrob. Agents17:209–213.PubMedCrossRefGoogle Scholar
  115. Zurita, J., Ayabaca, J., Pavón, L., Espinosa, Y., Narváez, I., and Grupo REDNARBEC. 2001. Se detectan Enterococcus faecium resistentes a vancomicina en dos hospitales de Quito. Rev. Ecuat. Med. Crit. 2(2): http://www.medicosecuador.com/medicina_critica/rev_vol2_num2/se_detectana.html

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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Departamento de BiomedicinaInstituto de Investigaciones en Biomedicina y Ciencias Aplicadas, Universidad de OrienteCumaná. Edo. SucreVenezuela

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