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Second Malignancies and Other Long Term Effects in Retinoblastoma Survivors

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Retinoblastoma

Part of the book series: Pediatric Oncology ((PEDIATRICO))

Abstract

Retinoblastoma is a cancer in the very young, and patients are very susceptible to the long term effects that the disease and the treatments administered may have in organ development and function. More importantly, patients with bilateral retinoblastoma are born with a germ-line mutation of the RB1 gene, probably the most potent tumor suppressor gene, and are at risk of developing cancers throughout their lives; in this regard, retinoblastoma may be just the beginning.

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Authors and Affiliations

  1. Dana-Farber Cancer Institute and Children’s Hospital Harvard Medical School, Boston, MA, USA

    C. Rodriguez-Galindo (Associate Professor of Pediatrics)

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  1. C. Rodriguez-Galindo
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Correspondence to C. Rodriguez-Galindo .

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Editors and Affiliations

  1. Dana-Farber Cancer Institute &, Harvard Medical School, Binney St. 44, Boston, 02115, U.S.A.

    Carlos Rodriguez-Galindo

  2. Hamilton Eye Inst., University of Tennessee, Madison Avenue 930, Memphis, 38103, U.S.A.

    Matthew W. Wilson

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Rodriguez-Galindo, C. (2010). Second Malignancies and Other Long Term Effects in Retinoblastoma Survivors. In: Rodriguez-Galindo, C., Wilson, M. (eds) Retinoblastoma. Pediatric Oncology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-89072-2_9

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  • DOI: https://doi.org/10.1007/978-0-387-89072-2_9

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