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Clinical Features, Diagnosis, Pathology

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Retinoblastoma

Part of the book series: Pediatric Oncology ((PEDIATRICO))

Abstract

This chapter will review the clinical and histopathologic features associated with the presentation and diagnosis of retinoblastoma. A thorough appreciation of the differential and a detailed clinical assessments is the cornerstone of arriving at the proper diagnosis. Unlike most cancers, retinoblastoma is unique, as tissue is generally not necessary for diagnostic and treatment purposes. However, once the eye is enucleated, the histopathologic features guide therapy and prognosis. We will review ancillary testing that can assist the clinician and address pathologic features that can affect patient prognosis.

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Author information

Authors and Affiliations

  1. Department of Pathology, The Methodist Hospital Weill College of Medicine of Cornell University, Houston, TX, USA

    P. Chévez-Barrios (Associate Professor of Pathology and Laboratory Medicine)

  2. Department of Head and Neck Surgery Section of Ophthalmology, The University of Texas MD. Anderson Cancer Center, Houston, TX, USA

    D. S. Gombos (Associate Professor of Ophthalmology)

Authors
  1. P. Chévez-Barrios
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  2. D. S. Gombos
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Corresponding author

Correspondence to P. Chévez-Barrios .

Editor information

Editors and Affiliations

  1. Dana-Farber Cancer Institute &, Harvard Medical School, Binney St. 44, Boston, 02115, U.S.A.

    Carlos Rodriguez-Galindo

  2. Hamilton Eye Inst., University of Tennessee, Madison Avenue 930, Memphis, 38103, U.S.A.

    Matthew W. Wilson

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Chévez-Barrios, P., Gombos, D.S. (2010). Clinical Features, Diagnosis, Pathology. In: Rodriguez-Galindo, C., Wilson, M. (eds) Retinoblastoma. Pediatric Oncology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-89072-2_3

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  • DOI: https://doi.org/10.1007/978-0-387-89072-2_3

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  • Print ISBN: 978-0-387-89071-5

  • Online ISBN: 978-0-387-89072-2

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