A Genetic Classifier Account for the Regulation of Expression
This work is motivated by our model of neuroscience processing which incorporates large numbers of reentrant top-down feedback regulation connections. Such regulation is fundamental and can be found throughout biology. The purpose of this chapter is to broaden this model's application.
Genes perform important life functions, responsible for virtually every organic molecule that organisms produce. The genes must closely regulate the amount of their products, because too little or too much production may be deleterious for the organism. Furthermore, they must respond efficiently and in unison to the environments that the organism faces. Networks that are closely regulated can behave as robust classifiers which can recognize and respond to their environment. Using simple examples we demonstrate that such networks perform dynamic classification, determining the most efficient set of genes needed to replace consumed products.
KeywordsConsumption Pattern Control Gene Expression Product Consumption Deleterious Gene Communal Equilibrium
I would like to thank Eyal Amir, Satwik Rajaram, Frances R. Wang, Tal Raveh, Cyrus Omar, and Robert Lee DeVille for helpful suggestions. This work was supported by the US National Geospatial Agency Grant HM1582-06–BAA-0001.
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