Intrathecal pumps are an option that allows patients who suffer from moderate-to-severe pain to have an improvement in quality of life, reduction in pain, and change in function. They also are an option for patients who are at the end of life to improve alertness, reduce fatigue and nausea, and improve survival. Unfortunately, despite the many positive attributes of these devices, they are not without risks. The complications can be classified as surgical, device related or drug related. This chapter focuses on the complications of intrathecal drug delivery, and on options to assess and reduce risks.
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