Chemical Peels for Precancerous Skin Lesions

  • Gary D. Monheit
  • Chad L. Prather


The use of chemoexfoliating agents to peel the epidermis and superficial dermis dates as far back as ancient Egypt, where sour milk baths were once used to soothe the skin. History has recorded the use of such chemicals as salt, sulfur, and various animal oils to exfoliate the skin for therapeutic and cosmetic purposes.1 The modern era of chemoexfoliation began in the early twentieth century, with phenol used as a peeling agent for post-acne scarring.


Stratum Corneum Precancerous Lesion Actinic Keratose Seborrheic Dermatitis Fitzpatrick Skin Type 
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  1. 1.
    Brody HJ, Monheit GD, Resnick SS, Alt TH. A history of chemical peeling. Dermatol Surg. 2000;26:405–409.CrossRefPubMedGoogle Scholar
  2. 2.
    Mackee GM, Karp FL. The treatment of post-acne scars with phenol. Br J Dermatol. 1952;64:456.CrossRefPubMedGoogle Scholar
  3. 3.
    Baker TJ, Gordon HL. Chemical face peeling: an adjunct to surgical facelifting. South Med J. 1963;56:412–414.CrossRefPubMedGoogle Scholar
  4. 4.
    Brody HJ. Variations and comparisons in medium depth chemical peeling. J Dermatol Surg Oncol. 1989;15:953–963.PubMedGoogle Scholar
  5. 5.
    Monheit GD. The Jessner's + TCA peel: a medium depth chemical peel. J Dermatol Surg Oncol. 1989;15:945–950.PubMedGoogle Scholar
  6. 6.
    Coleman WP, Futrell JM. The glycolic acid trichloroacetic acid peel. J Dermatol Surg Oncol. 1994;20:76–80.PubMedGoogle Scholar
  7. 7.
    2007 American Academy of Dermatology Survey. “Majority of dermatologists are providing cosmetic services”. Skin & Allergy News. February 2008:29.Google Scholar
  8. 8.
    Stegman SJ. A comparative histologic study of the effects of three peeling agents and dermabrasion on normal and sun-damaged skin. Aesthetic Plast Surg. 1982;6:123–125.CrossRefPubMedGoogle Scholar
  9. 9.
    Glogau RG. Chemical peeling and aging skin. J Geriatr Dermatol. 1994;2(1):30–35.Google Scholar
  10. 10.
    Coleman WP. Dermabrasion and hypertrophic scars. Int J Dermatol. 1991;30(9):629–631.CrossRefPubMedGoogle Scholar
  11. 11.
    Monheit GD. The Jessner's-trichloroacetic acid peel. Dermatol Clin. 1995;13(2):277–283.PubMedGoogle Scholar
  12. 12.
    Brody HJ. Trichloroacetic acid application in chemical peeling, operative techniques. Plast Reconstr Surg. 1995;2(2):127–128.Google Scholar
  13. 13.
    Monheit GD. Chemical peeling for pigmentary dyschromias. Cosmetic Dermatol. 1995;8(5):10–15.Google Scholar
  14. 14.
    Monheit GD. Presentation at the American Academy of Dermatology in New Orleans. March 25, 1999.Google Scholar
  15. 15.
    Rubin M. Manual of Chemical Peels. Philadelphia: Lippincott; 1995:120–121.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Gary D. Monheit
    • 1
  • Chad L. Prather
    • 2
  1. 1.Department of Dermatology and Ophthalmology, Total Skin and Beauty Dermatology CenterUniversity of AlabamaBirminghamUSA
  2. 2.Department of DermatologyLouisiana State University School of MedicineNew OrleansUSA

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