- 1.The fundamentals of a cohort study design are:
Identify people who are free of disease at the beginning of the study
Assemble cohorts of exposed and unexposed individuals
Follow cohorts for the development of incident outcomes
Compare the risks of incident outcomes in each cohort
- 2.Cohort studies have certain advantages:
Can discern temporal relationships between the exposure and the outcome
Can be used to evaluate multiple outcomes
- 3.Cohort studies have certain disadvantages:
Observational design: other factors may be responsible for observed association
May be inefficient for studying rare diseases or those with long latency periods
Cohort studies can be used to evaluate the risks and benefits of medication use.
Cohort studies can be used to calculate relative and attributable risks of disease.
KeywordsHormone Replacement Therapy Kidney Transplant Peripheral Arterial Disease Attributable Risk Serum Retinol
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