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Reproductive Endocrinology pp 145–160Cite as

FSH: One Hormone with Multiple Forms, or a Family of Multiple Hormones

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Follicle stimulating hormone (FSH) is produced within pituitary gonadotroph cells and is a critical component of the reproductive process. It has a wide variety of activities in both male and female reproductive tissues including growth, division, and differentiation of Sertoli and granulosa cells. As a result, FSH is directly involved in the production of both male and female gametes, as well as production of hormones (estradiol and inhibin) that feed back to influence secretion of FSH from the pituitary.

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Author information

Authors and Affiliations

  1. Department of Animal Sciences & Industry, Kansas State University, Manhattan, KS, USA

    Tim G. Rozell

  2. Cytogenetics Laboratory, Royal University Hospital, Saskatoon, SK, Canada

    Rena J. Okrainetz

Authors
  1. Tim G. Rozell
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  2. Rena J. Okrainetz
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Editors and Affiliations

     

    ACTH:

    adrenocorticotropic hormone

    ALK4:

    activin receptor-like kinase 4

    Asn:

    asparagine

    cAMP:

    cyclic adenosine monophosphate

    CGA:

    common glycoprotein alpha

    CHO cells:

    Chinese hamster ovary cells

    FSH:

    follicle stimulating hormone

    GalNAc:

    N-acetylgalactosamine

    GlcNAc:

    N-acetylglucosamine

    GnRH:

    gonadotropin releasing hormone, or LHRH – luteinizing hormone releasing hormone

    hCG:

    human chorionic gonadotropin

    HEK-293 cells:

    human embryonic kidney cells

    hMG:

    human menopausal gonadotropin

    IP3:

    inositol 1,4,5-triphosphate

    LH:

    luteinizing hormone

    MAPK:

    mitogen-activated protein kinase

    PACAP:

    pituitary adenylate cyclase-activating polypeptide

    PDGF:

    platelet-derived growth factor

    PKC:

    protein kinase C

    PRE:

    progesterone response element

    RER:

    rough endoplasmic reticulum

    rFSH:

    recombinant follicle stimulating hormone

    TGF-β:

    transforming growth factor-β

    TSH:

    thyroid stimulating hormone

    UTR:

    untranslated region

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    © 2009 Springer Science+Business Media, LLC

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    Rozell, T.G., Okrainetz, R.J. (2009). FSH: One Hormone with Multiple Forms, or a Family of Multiple Hormones. In: Chedrese, P. (eds) Reproductive Endocrinology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-88186-7_14

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    • DOI: https://doi.org/10.1007/978-0-387-88186-7_14

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