FSH: One Hormone with Multiple Forms, or a Family of Multiple Hormones

  • Tim G. Rozell
  • Rena J. Okrainetz

Follicle stimulating hormone (FSH) is produced within pituitary gonadotroph cells and is a critical component of the reproductive process. It has a wide variety of activities in both male and female reproductive tissues including growth, division, and differentiation of Sertoli and granulosa cells. As a result, FSH is directly involved in the production of both male and female gametes, as well as production of hormones (estradiol and inhibin) that feed back to influence secretion of FSH from the pituitary.


Luteinizing Hormone Granulosa Cell Follicle Stimulate Hormone GnRH Receptor Glycoprotein Hormone 


14.10Glossary of Terms and Acronyms


adrenocorticotropic hormone


activin receptor-like kinase 4




cyclic adenosine monophosphate


common glycoprotein alpha

CHO cells:

Chinese hamster ovary cells


follicle stimulating hormone






gonadotropin releasing hormone, or LHRH – luteinizing hormone releasing hormone


human chorionic gonadotropin

HEK-293 cells:

human embryonic kidney cells


human menopausal gonadotropin


inositol 1,4,5-triphosphate


luteinizing hormone


mitogen-activated protein kinase


pituitary adenylate cyclase-activating polypeptide


platelet-derived growth factor


protein kinase C


progesterone response element


rough endoplasmic reticulum


recombinant follicle stimulating hormone


transforming growth factor-β


thyroid stimulating hormone


untranslated region


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Tim G. Rozell
    • 1
  • Rena J. Okrainetz
    • 2
  1. 1.Department of Animal Sciences & IndustryKansas State UniversityManhattanUSA
  2. 2.Cytogenetics Laboratory, Royal University HospitalSaskatoonCanada

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