Health-Related Quality of Life Instruments for Adolescents with Chronic Diseases

  • Alexandra L. Quittner
  • Ivette Cruz
  • Avani C. Modi
  • Kristen K. Marciel

Over the past two decades, tremendous progress has been made in defining and measuring health-related quality of life (HRQOL) and in recognizing its importance as a health outcome (Palermo et al., 2008; Quittner, Davis, & Modi, 2003). More than 50 years ago, the World Health Organization proposed the first definition of HRQOL as “a state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity” (World Health Organization [WHO], 1947, p. 29). A consensus definition of HRQOL has now emerged, with agreement that it is multidimensional and includes four core domains: (1) disease state and physical symptoms, (2) functional status (e.g., performing daily activities), (3) psychological and emotional functioning, and (4) social functioning (Hays, 2005; Rothman et al., 2007).


Internal Consistency Cystic Fibrosis Convergent Validity Good Internal Consistency Minimal Clinically Important Difference 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Alexandra L. Quittner
    • 1
  • Ivette Cruz
    • 1
  • Avani C. Modi
    • 2
  • Kristen K. Marciel
  1. 1.Department of Psychology & PediatricsUniversity of MiamiMiamiUSA
  2. 2.Division of Behavioral Medicine and Clinical PsychologyCincinnati Children’s HospitalCincinnatiUSA

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