Integrated Care Practice Guidelines for Adolescents with Asthma


Asthma is a complex disease process involving obstruction of the airway passages, which on occasion can lead to death. It is the most common chronic disease of childhood. The National Asthma Education and Prevention Program’s Expert Panel Report-3 (“Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007,” 2007) more directly defines asthma as.


Atopic Dermatitis Allergic Rhinitis Panic Disorder Asthma Symptom Asthma Management 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Abramson, N. W., Wamboldt, F. S., Mansell, A. L., Carter, R., Federico, M. J., & Wamboldt, M. Z. (2008). Frequency and correlates of overweight status in adolescent asthma. Journal of Asthma, 45(2), 135–139.PubMedCrossRefGoogle Scholar
  2. Akinbami, L. (2006). The state of childhood asthma, United States, 1980–2005. Advance Data, (381), 1–24.Google Scholar
  3. Amelung, P. J., Scott, A. F., & Bleecker, E. R. (1996). Genetic of bronchial hyperresponsiveness. In S. B. Liggett & D. A. Meyers (Eds.). The Genetics of Asthma (Vol. 96, pp. 525–540). New York City: Marcel Dekker, Inc.Google Scholar
  4. Arshad, S. H., & Hide, D. W. (1992). Effect of environmental factors on the development of allergic disorders in infancy. Journal of Allergy and Clinical Immunology, 90(2), 235–241.PubMedCrossRefGoogle Scholar
  5. Balkissoon, R. (2007). Vocal cord dysfunction, gastroesophageal reflux disease, and nonallergic rhinitis. Clinical Allergy and Immunology, 19, 411–426.PubMedGoogle Scholar
  6. Barnes, N. C. (2007). The properties of inhaled corticosteroids: Similarities and differences. Primary Care Respiratory Journal, 16(3), 149–154.PubMedCrossRefGoogle Scholar
  7. Beckett, W. S., Belanger, K., Gent, J. F., Holford, T. R., & Leaderer, B. P. (1996). Asthma among Puerto Rican Hispanics: A multi-ethnic comparison study of risk factors. American Journal of Respiratory and Critical Care Medicine, 154(4 Pt 1), 894–899.PubMedGoogle Scholar
  8. Bender Berz, J., Murdock, K. K., & Koinis Mitchell, D. (2005). Children's asthma, internalizing problems, and social functioning: An urban perspective. Journal of Child and Adolescent Psychiatric Nursing, 18(4), 181–197.PubMedCrossRefGoogle Scholar
  9. Blackman, J. A., & Gurka, M. J. (2007). Developmental and behavioral comorbidities of asthma in children. Journal of Developmental and Behavioral Pediatrics, 28(2), 92–99.PubMedCrossRefGoogle Scholar
  10. Blackwell, D. L., Collins, J. G., & Coles, R. (2002). Summary health statistics for U.S. adults: National Health Interview Survey, 1997. Vital & Health Statistics, 10(205), 1–109.Google Scholar
  11. Block, J. H., Block, J., & Morrison, A. (1981). Parental agreement–disagreement on child-rearing orientations and gender-related personality correlates in children. Child Development, 52(3), 10.Google Scholar
  12. Bloom, B., & Cohen, R. A. (2007). Summary health statistics for U.S. children: National Health Interview Survey, 2006. Vital & Health Statistics, 10(234), 1–79.Google Scholar
  13. Bosse, Y., Pare, P. D., & Seow, C. Y. (2008). Airway wall remodeling in asthma: From the epithelial layer to the adventitia. Current Allergy and Asthma Reports, 8(4), 357–366.PubMedCrossRefGoogle Scholar
  14. Bousquet, J., Clark, T. J., Hurd, S., Khaltaev, N., Lenfant, C., O'Byrne, P., et al. (2007). GINA guidelines on asthma and beyond. Allergy, 62(2), 102–112.PubMedGoogle Scholar
  15. Bussing, R., Burket, R. C., & Kelleher, E. T. (1996). Prevalence of anxiety disorders in a clinic-based sample of pediatric asthma patients. Psychosomatics, 37(2), 108–115.PubMedGoogle Scholar
  16. Carpentier, M. Y., Mullins, L. L., & Van Pelt, J. C. (2007). Psychological, academic, and work functioning in college students with childhood-onset asthma. Journal of Asthma, 44(2), 119–124.PubMedCrossRefGoogle Scholar
  17. Carroll, C. L., & Zucker, A. R. (2007). The increased cost of complications in children with status asthmaticus. Pediatric Pulmonology, 42(10), 914–919.PubMedCrossRefGoogle Scholar
  18. CDC. (2008). Asthma: Children and adolescents | CDC APRHB. From
  19. Center for Disease Control and Prevention, Self-reported asthma prevalence among adults – United States, 2000. (2001). Morbidity and Mortality Weekly Report, 50(32), 682–686.Google Scholar
  20. Craske, M. G., Poulton, R., Tsao, J. C., & Plotkin, D. (2001). Paths to panic disorder/agoraphobia: An exploratory analysis from age 3 to 21 in an unselected birth cohort. Journal of the American Academy of Child and Adolescent Psychiatry, 40(5), 556–563.PubMedCrossRefGoogle Scholar
  21. Denson-Lino, J. M., Willies-Jacobo, L. J., Rosas, A., O'Connor, R. D., & Wilson, N. W. (1993). Effect of economic status on the use of house dust mite avoidance measures in asthmatic children. Annals of Allergy, 71(2), 130–132.PubMedGoogle Scholar
  22. Duffy, D. L., Martin, N. G., Battistutta, D., Hopper, J. L., & Mathews, J. D. (1990). Genetics of asthma and hay fever in Australian twins. American Review of Respiratory Disease, 142(6 Pt 1), 1351–1358.PubMedGoogle Scholar
  23. Edfors-Lubs, M. L. (1971). Allergy in 7000 twin pairs. Acta Allergologica, 26(4), 249–285.PubMedGoogle Scholar
  24. Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. (2007). Journal of Allergy and Clinical Immunology, 120(5 Suppl), S94–138.Google Scholar
  25. Federico, M. J., Wamboldt, F. S., Carter, R., Mansell, A., & Wamboldt, M. Z. (2007). History of serious asthma exacerbations should be included in guidelines of asthma severity. Journal of Allergy and Clinical Immunology, 119(1), 50–56.PubMedCrossRefGoogle Scholar
  26. Fiese, B. H., Wamboldt, F. S., & Anbar, R. D. (2005). Family asthma management routines: Connections to medical adherence and quality of life. Journal of Pediatrics, 146(2), 171–176.PubMedGoogle Scholar
  27. Forrest, C. B., Starfield, B., Riley, A. W., & Kang, M. (1997). The impact of asthma on the health status of adolescents. Pediatrics, 99(2), E1.PubMedCrossRefGoogle Scholar
  28. Galobardes, B., McCarron, P., Jeffreys, M., & Davey Smith, G. (2008). Association between early life history of respiratory disease and morbidity and mortality in adulthood. Thorax, 63(5), 423–429.PubMedCrossRefGoogle Scholar
  29. Getahun, D., Demissie, K., & Rhoads, G. G. (2005). Recent trends in asthma hospitalization and mortality in the United States. Journal of Asthma, 42(5), 373–378.PubMedCrossRefGoogle Scholar
  30. Glazebrook, C., McPherson, A. C., Macdonald, I. A., Swift, J. A., Ramsay, C., Newbould, R., et al. (2006). Asthma as a barrier to children's physical activity: Implications for body mass index and mental health. Pediatrics, 118(6), 2443–2449.PubMedCrossRefGoogle Scholar
  31. Goodwin, R. D., Fergusson, D. M., & Horwood, L. J. (2004). Asthma and depressive and anxiety disorders among young persons in the community. Psychological Medicine, 34(8), 1465–1474.PubMedCrossRefGoogle Scholar
  32. Goodwin, R. D., Pine, D. S., & Hoven, C. W. (2003). Asthma and panic attacks among youth in the community. Journal of Asthma, 40(2), 139–145.PubMedCrossRefGoogle Scholar
  33. Hardie, G. E., Janson, S., Gold, W. M., Carrieri-Kohlman, V., & Boushey, H. A. (2000). Ethnic differences: Word descriptors used by African-American and white asthma patients during induced bronchoconstriction. Chest, 117(4), 935–943.PubMedCrossRefGoogle Scholar
  34. Heinrich, J., Hoelscher, B., Frye, C., Meyer, I., Wjst, M., & Wichmann, H. E. (2002). Trends in prevalence of atopic diseases and allergic sensitization in children in Eastern Germany. European Respiratory Journal, 19(6), 1040–1046.PubMedCrossRefGoogle Scholar
  35. Ho, J., Bender, B. G., Gavin, L. A., O'Connor, S. L., Wamboldt, M. Z., & Wamboldt, F. S. (2003). Relations among asthma knowledge, treatment adherence, and outcome. Journal of Allergy and Clinical Immunology, 111(3), 498–502.PubMedCrossRefGoogle Scholar
  36. Horner, C. C., & Strunk, R. C. (2007). Age-related changes in the asthmatic phenotype in children. Current Opinion in Pediatrics, 19(3), 295–299.PubMedCrossRefGoogle Scholar
  37. Horwood, L. J., Fergusson, D. M., & Shannon, F. T. (1985). Social and familial factors in the development of early childhood asthma. Pediatrics, 75(5), 859–868.PubMedGoogle Scholar
  38. Humbert, M., Holgate, S., Boulet, L. P., & Bousquet, J. (2007). Asthma control or severity: That is the question. Allergy, 62(2), 95–101.PubMedGoogle Scholar
  39. Juniper, E. F., Guyatt, G. H., Feeny, D. H., Ferrie, P. J., Griffith, L. E., & Townsend, M. (1996). Measuring quality of life in children with asthma. Quality of Life Research, 5(1), 35–46.PubMedCrossRefGoogle Scholar
  40. Kasasbeh, A., Kasasbeh, E., & Krishnaswamy, G. (2007). Potential mechanisms connecting asthma, esophageal reflux, and obesity/sleep apnea complex – a hypothetical review. Sleep Medicine Reviews, 11(1), 47–58.PubMedCrossRefGoogle Scholar
  41. Kashani, J. H., Konig, P., Shepperd, J. A., Wilfley, D., & Morris, D. A. (1988). Psychopathology and self-concept in asthmatic children. Journal of Pediatric Psychology, 13(4), 509–520.PubMedCrossRefGoogle Scholar
  42. Katon, W., Lozano, P., Russo, J., McCauley, E., Richardson, L., & Bush, T. (2007). The prevalence of DSM-IV anxiety and depressive disorders in youth with asthma compared with controls. Journal of Adolescent Health, 41(5), 455–463.PubMedCrossRefGoogle Scholar
  43. Kean, E. M., Kelsay, K., Wamboldt, F., & Wamboldt, M. Z. (2006). Posttraumatic stress in adolescents with asthma and their parents. Journal of the American Academy of Child and Adolescent Psychiatry, 45(1), 78–86.PubMedCrossRefGoogle Scholar
  44. Klinnert, M. D., Kaugars, A. S., Strand, M., & Silveira, L. (2008). Family psychological factors in relation to children's asthma status and behavioral adjustment at age 4. Family Process, 47(1), 41–61.PubMedCrossRefGoogle Scholar
  45. Koh, M. S., & Irving, L. B. (2007). The natural history of asthma from childhood to adulthood. International Journal of Clinical Practice, 61(8), 1371–1374.PubMedCrossRefGoogle Scholar
  46. Liggett, S. B. (1996). The genetics of beta 2-andrenergic receptor polymorphisms: Relevance to receptor function and asthmatic phenotypes. In S. B. Liggett & D. A. Meyers (Eds.). The Genetics of Asthma (Vol. 96, pp. 455–474). New York City: Marcel Dekker, Inc.Google Scholar
  47. Lougheed, M. D., Fisher, T., & O'Donnell, D. E. (2006). Dynamic hyperinflation during bronchoconstriction in asthma: Implications for symptom perception. Chest, 130(4), 1072–1081.PubMedCrossRefGoogle Scholar
  48. Malveaux, F. J., & Fletcher-Vincent, S. A. (1995). Environmental risk factors of childhood asthma in urban centers. Environmental Health Perspectives, 103(Suppl 6), 59–62.PubMedCrossRefGoogle Scholar
  49. Mansfield, L. E. (2008). The future of the long-acting beta-adrenergic bronchodilators in the treatment of asthma. Allergy and Asthma Proceedings, 29(2), 103–108.Google Scholar
  50. Marion, R. J., Creer, T. L., & Reynolds, R. V. (1985). Direct and indirect costs associated with the management of childhood asthma. Annals of Allergy, 54(1), 31–34.PubMedGoogle Scholar
  51. McQuaid, E. L., Walders, N., Kopel, S. J., Fritz, G. K., & Klinnert, M. D. (2005). Pediatric asthma management in the family context: The family asthma management system scale. Journal of Pediatric Psychology, 30(6), 492–502.PubMedCrossRefGoogle Scholar
  52. Mohangoo, A. D., de Koning, H. J., Mangunkusumo, R. T., & Raat, H. (2007). Health-related quality of life in adolescents with wheezing attacks. Journal of Adolescent Health, 41(5), 464–471.PubMedCrossRefGoogle Scholar
  53. Moonie, S., Sterling, D. A., Figgs, L. W., & Castro, M. (2008). The relationship between school absence, academic performance, and asthma status. Journal of School Health, 78(3), 140–148.PubMedCrossRefGoogle Scholar
  54. Moorman, J. E., Rudd, R. A., Johnson, C. A., King, M., Minor, P., Bailey, C., et al. (2007). National surveillance for asthma – United States, 1980–2004. MMWR Surveillance Summaries, 56(8), 1–54.Google Scholar
  55. Morgan, M., & Khan, D. A. (2003). Asthma: Epidemiology, burden, and quality of life. In E. S. Brown (Ed.). Asthma: Social and psychological factors and psychosomatic syndromes (Vol. 24, pp. 1–15). Basel: Karger.Google Scholar
  56. Mrazek, D., & Strunk, R. (1984). Psychological adjustment of severely asthmatic preschool children: Allergic considerations. Psychosom Med, 46.Google Scholar
  57. National Heart, Lung, and Blood Institute. (1995). NHLBI/WHO Workshop Report: Global strategy for asthma management and prevention. Global Initiative for Asthma. Bethesda, MD: Author. Publication No. 95-3659.Google Scholar
  58. National Heart Lung and Blood Institute Asthma Signs and Symptoms of Asthma. (2008) from
  59. Ortega, A. N., Huertas, S. E., Canino, G., Ramirez, R., & Rubio-Stipec, M. (2002). Childhood asthma, chronic illness, and psychiatric disorders. Journal of Nervous and Mental Disease, 190(5), 275–281.PubMedGoogle Scholar
  60. Ortega, A. N., McQuaid, E. L., Canino, G., Ramirez, R., Fritz, G. K., & Klein, R. B. (2003). Association of psychiatric disorders and different indicators of asthma in island Puerto Rican children. Social Psychiatry and Psychiatric Epidemiology, 38(4), 220–226.PubMedCrossRefGoogle Scholar
  61. Pearlman, D. N., Zierler, S., Meersman, S., Kim, H. K., Viner-Brown, S. I., & Caron, C. (2006). Race disparities in childhood asthma: Does where you live matter? Journal of the National Medical Association, 98(2), 239–247.PubMedGoogle Scholar
  62. Purcell, K., Turnbull, J. W., & Bernstein, L. (1962). Distinctions between subgroups of asthmatic children: Psychological test and behavior rating comparisons. Journal of Psychosomatic Research, 6, 283–291.PubMedCrossRefGoogle Scholar
  63. Rand, C. S., & Wise, R. A. (1994). Measuring adherence to asthma medication regimens. American Journal of Respiratory and Critical Care Medicine, 149(2 Pt 2), S69-76; discussion S77-68.PubMedGoogle Scholar
  64. Reed, C. E. (2006). The natural history of asthma. Journal of Allergy and Clinical Immunology, 118(3), 543–548; quiz 549–550.PubMedCrossRefGoogle Scholar
  65. Restrepo, R. D., & Peters, J. (2008). Near-fatal asthma: Recognition and management. Current Opinion in Pulmonary Medicine, 14(1), 13–23.PubMedCrossRefGoogle Scholar
  66. Rhee, H., Wenzel, J., & Steeves, R. H. (2007). Adolescents' psychosocial experiences living with asthma: A focus group study. Journal of Pediatric Health Care, 21(2), 99–107.PubMedCrossRefGoogle Scholar
  67. Rosier, M. J., Bishop, J., Nolan, T., Robertson, C. F., Carlin, J. B., & Phelan, P. D. (1994). Measurement of functional severity of asthma in children. American Journal of Respiratory and Critical Care Medicine, 149(6), 1434–1441.PubMedGoogle Scholar
  68. Silverglade, L., Tosi, D. J., Wise, P. S., & D'Costa, A. (1994). Irrational beliefs and emotionality in adolescents with and without bronchial asthma. Journal of General Psychology, 121(3), 199–207.PubMedCrossRefGoogle Scholar
  69. Strunk, R. C., Mrazek, D. A., Fuhrmann, G. S., & LaBrecque, J. F. (1985). Physiologic and psychological characteristics associated with deaths due to asthma in childhood. A case-controlled study. Journal of the American Medical Association, 254(9), 1193–1198.PubMedCrossRefGoogle Scholar
  70. Taras, H., & Potts-Datema, W. (2005). Childhood asthma and student performance at school. Journal of School Health, 75(8), 296–312.PubMedGoogle Scholar
  71. Trends in asthma morbidity and mortality by American Lung Association Epidemiology and Statistics Unit Research and Program Services July 2006. (2006). from{7A8D42C2-FCCA-4604-8ADE-7F5D5E762256}/ASTHMA06FINAL.PDF
  72. Vila, G., Nollet-Clemencon, C., de Blic, J., Mouren-Simeoni, M. C., & Scheinmann, P. (2000). Prevalence of DSM IV anxiety and affective disorders in a pediatric population of asthmatic children and adolescents. Journal of Affective Disorders, 58(3), 223–231.PubMedCrossRefGoogle Scholar
  73. Vila, G., Nollet-Clemencon, C., Vera, M., Robert, J. J., de Blic, J., Jouvent, R., et al. (1999). Prevalence of DSM-IV disorders in children and adolescents with asthma versus diabetes. Canadian Journal of Psychiatry, 44(6), 562–569.Google Scholar
  74. Wamboldt, F. S., Ho, J., Milgrom, H., Wamboldt, M. Z., Sanders, B., Szefler, S. J., et al. (2002). Prevalence and correlates of household exposures to tobacco smoke and pets in children with asthma. Journal of Pediatrics, 141(1), 109–115.PubMedGoogle Scholar
  75. Wamboldt, F. S., Wamboldt, M. Z., Gavin, L. A., Roesler, T. A., & Brugman, S. M. (1995). Parental criticism and treatment outcome in adolescents hospitalized for severe, chronic asthma. Journal of Psychosomatic Research, 39(8), 995–1005.PubMedCrossRefGoogle Scholar
  76. Wamboldt, M. Z., & Levin, L. (1995). Utility of multifamily psychoeducational groups for medically ill children and adolescents. Family Systems Medicine, 13(2), 151–161.CrossRefGoogle Scholar
  77. Wamboldt, M. Z., & Weintraub, P. (1995). Links between past parental trauma and the medical and psychological outcome of asthmatic children: A theoretical model. Family Systems Medicine, 13(2), 129–149.CrossRefGoogle Scholar
  78. Wamboldt, M. Z., Yancey, A. G., Jr., & Roesler, T. A. (1997). Cardiovascular effects of tricyclic antidepressants in childhood asthma: A case series and review. Journal of Child and Adolescent Psychopharmacology, 7(1), 45–64.PubMedCrossRefGoogle Scholar
  79. Willis, D. J. (2002). Introduction to the special issue: economic, health, and mental health disparities among ethnic minority children and families. Journal of Pediatric Psychology, 27(4), 309–314.PubMedCrossRefGoogle Scholar
  80. Willwerth, B. M., Schaub, B., Tantisira, K. G., Gold, D. R., Palmer, L. J., Litonjua, A. A., et al. (2006). Prenatal, perinatal, and heritable influences on cord blood immune responses. Annals of Allergy Asthma & Immunology, 96(3), 445–453.CrossRefGoogle Scholar
  81. Wood, B. L., Lim, J., Miller, B. D., Cheah, P. A., Simmens, S., Stern, T., et al. (2007). Family emotional climate, depression, emotional triggering of asthma, and disease severity in pediatric asthma: Examination of pathways of effect. Journal of Pediatric Psychology, 32(5), 542–551.PubMedGoogle Scholar
  82. Wood, B. L., Lim, J., Miller, B. D., Cheah, P., Zwetsch, T., Ramesh, S., et al. (2008). Testing the Biobehavioral Family Model in pediatric asthma: Pathways of effect. Family Process, 47(1), 21–40.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Department of PsychiatryThe Children’s Hospital, University of Colorado at Denver and Health Sciences CenterAuroraUSA
  2. 2.University of Colorado at Denver and Health Sciences CenterAuroraUSA

Personalised recommendations