Nonopioid Analgesics in Pain Management

  • Jack M. Berger
  • Shaaron Zaghi


Since patients rarely present with pure nociceptive pain (i.e., pain caused by activity in the neural pathways in response to damaging or potentially damaging stimuli) or neuropathic pain (i.e., pain initiated by a primary lesion or dysfunction in the nervous system), but rather suffer a mixed pain syndrome (i.e., pain caused by a combination of both the primary injury and secondary effects), a rational polypharmacy approach that targets key peripheral and central pain mechanisms and modulating pathways may yield the best outcomes (Management of Chronic Pain Syndromes 2005).


Neuropathic Pain Pain Management Trigeminal Neuralgia Complex Regional Pain Syndrome Diabetic Peripheral Neuropathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Jack M. Berger
    • 1
  • Shaaron Zaghi
    • 2
  1. 1.Keck School of MedicineUniversity of Southern CaliforniaLos AngelesUSA
  2. 2.Department of AnesthesiologyUniversity of Southern California Keck School of MedicineLos AngelesUSA

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