Importance of Placebo Effect in Pain Management

  • Charles Brown
  • Paul J. Christo


The word placebo is derived from the Latin verb “to please” and, as early as 1811, appeared in the Hooper’s Medical Dictionary as a medical treatment aimed at pleasing – a placebo was defined as “an epithet given to any medication adopted more to please than to benefit the patient (Hooper 1817).” In the modern day era, Tilburt et al. refer to the placebo effect as “positive clinical outcomes caused by a treatment that is not attributable to its known physical properties or mechanism of action (Tilburt et al. 2008).”


Conditioned Stimulus Placebo Effect Placebo Response Chronic Pain Patient Endogenous Opioid 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Charles Brown
    • 1
  • Paul J. Christo
    • 1
  1. 1.Division of Pain Medicine, Department of Anesthesiology and Critical Care MedicineThe Johns Hopkins University School of MedicineBaltimoreUSA

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