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Lung Transplantation for Pulmonary Hypertension

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Textbook of Pulmonary Vascular Disease
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Abstract

Lung transplantation is an effective although imperfect therapy for end-stage lung disease. As medical therapeis improve the prognosis of patients with pulmonary hypertension, use of lung transplantation for primary pulmonary hypertension has declined. Nonetheless, it remains the last life-saving option for properly selected candidates. This chapter will review the surgical aspects of lung transplantation for pulmonary hypertension.

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References

  1. Reitz BA, Wallwork JL, Hunt SA et al (1982) Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease. N Engl J Med 306:557–564

    Article  PubMed  CAS  Google Scholar 

  2. Fremes SE, Patterson GA, Williams WG, Goldman BS, Todd TR, Maurer J (1990) Single lung transplantation and closure of patent ductus arteriosis for Eisenmenger’s syndrome; Toronto Lung Transplant Group. J Thorac Cardiovasc Surg 100:1–5

    PubMed  CAS  Google Scholar 

  3. Pasque MK, Cooper JD, Kaiser DA, Haydock DA, Triantafillou TEP (1990) Improved technique for bilateral lung transplantation: rationale and initial clinical experience. Ann Thorac Surg 49:785–791

    Article  PubMed  CAS  Google Scholar 

  4. Orens JB, Estenne M, Arascoy S et al (2006) International guidelines for the selection of lung transplant candidates; 2006 update – a consensus report from the pulmonary scientific council of the International Society of Heart and Lung Transplantation. J Heart Lung Transplant 25:745–755

    Article  PubMed  Google Scholar 

  5. Nwakanma LU, Simpkins CE, Williams JA et al (2007) Impact of bilateral versus single lung transplantation on survival in recipients 60 years of age and older: analysis of the United Network for Organ Sharing database. J Thorac Cardiovasc Surg 133:541–547

    Article  PubMed  Google Scholar 

  6. Miyamoto S, Nagaya N, Satoh T et al (2000) Clinical correlates and prognostic significance of six minute walk test in patients with primary pulmonary hypertension. Am J Respir Crit Care Med 161:487–492

    PubMed  CAS  Google Scholar 

  7. Mulligan MS, Shearon TH, Weill D, Pagani FD, Moore J, Murray S (2008) Heart and lung transplantation in the United States, 1997–2006. Am J Transplant 8:977–987

    Article  PubMed  CAS  Google Scholar 

  8. Hadjiliadis D, Chaparro C, Guitierrez C et al (2006) Impact of lung transplant operation on bronchiolotis obliterans syndrome in patients with chronic obstructive lung disease. Am J Transplant 6:183–189

    Article  PubMed  CAS  Google Scholar 

  9. Gammie JS, Pham SM, Colson YL et al (1998) Single versus double lung transplantation for pulmonary hypertension. J Thorac Cardiovasc Surg 115:397–402

    Article  PubMed  CAS  Google Scholar 

  10. Toyoda Y, Thacker J, Santos R et al (2008) Long-term outcome of lung and heart-lung transplantation for idiopathic pulmonary arterial hypertension. Ann Thorac Surg 86:1116–1122

    Article  PubMed  Google Scholar 

  11. Mason DP, Thuita L, Alster JM et al (2008) Should lung transplantation be performed using donation after cardiac death? The United States experience. J Thorac Cardiovasc Surg 136:1061–1066

    Article  PubMed  Google Scholar 

  12. Schnickel GT, Ross DJ, Beygui R et al (2006) Modified reperfusion in clinical lung transplantation: the results of 100 consecutive cases. J Thorac Cardiovasc Surg 131:218–223

    Article  PubMed  Google Scholar 

  13. Aigner C, Wisser W, Taghavi S et al (2007) Institutional experience with extracorporeal membrane oxygenation in lung transplantation. Eur J Cardiothorac Surg 31:468–473

    Article  PubMed  Google Scholar 

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Correspondence to Ashish S. Shah .

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Shah, A.S., Conte, J.V. (2011). Lung Transplantation for Pulmonary Hypertension. In: Yuan, JJ., Garcia, J., West, J., Hales, C., Rich, S., Archer, S. (eds) Textbook of Pulmonary Vascular Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-87429-6_116

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  • DOI: https://doi.org/10.1007/978-0-387-87429-6_116

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  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-87428-9

  • Online ISBN: 978-0-387-87429-6

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