Atherosclerosis of the Aorta and Prevention of Neurological Dysfunction After Cardiac Surgery

  • Fellery de Lange
  • G. Burkhard Mackensen
  • Madhav Swaminathan


On May 6, 1953, John H Gibbon Jr., a Philadelphia surgeon, performed the world’s first successful open heart procedure in which total heart–lung bypass was employed.1 Since that time, aortic manipulation and postoperative neurological complications have coexisted. Aortic atherosclerosis remains a significant marker of coronary artery disease, perioperative vascular events, stroke, and even renal dysfunction. Although cardiac surgery is unique in that manipulation of the ascending aorta is almost routine, surgical handling of a diseased aorta is not always without risk.


Aortic Arch Aortic Surgery Aortic Atherosclerosis Aortic Plaque Postoperative Stroke 


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Fellery de Lange
  • G. Burkhard Mackensen
  • Madhav Swaminathan
    • 1
  1. 1.Department of AnesthesiologyDuke University Medical CenterDurhamUSA

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