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Development of Macrophages and Granulocytes

  • Richard Dahl

Abstract

Myeloid cells (monocytes/macrophages and granulocytes) are derived from a common progenitor, the granulocyte—monocyte progenitor (GMP). Combinatorial interactions between hematopoietic transcription factors program the differentiation of the GMP into monocytes and the four granulocytic lineages: neutrophils, eosinophils, basophils, and mast cells. Cytokines and growth factors mainly function to promote proliferation and survival of the myeloid lineages. However, there is evidence demonstrating that cytokines can affect transcription factor expression and influence lineage commitment. Gene targeting experiments in mice have demonstrated that several transcription factors are required to specify distinct myeloid lineages. An essential role for cytokines in steady state hematopoiesis has not been observed; however, several cytokines are required to mobilize proper immune responses to infectious pathogens. A newly recognized class of small RNAs termed micro-RNAs (miRNAs) may be critical in lineage specification. These small RNA molecules regulate the translation of specific mRNAs. Recent research is beginning to support the role of miRNAs in lineage commitment by regulating the protein accumulation of specific hematopoietic transcription factors.

Keywords

Mast Cell Myeloid Cell Hematopoietic Progenitor Fetal Liver Cell bZIP Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Akashi, K., Traver, D., Miyamoto, T. & Weissman, I.L. (2000). Nature, 404, 193–7.PubMedGoogle Scholar
  2. Anderson, K.L., Smith, K.A., Pio, F., Torbett, B.E. & Maki, R.A. (1998). Blood, 92, 1576–85.PubMedGoogle Scholar
  3. Anderson, K.L., Smith, K.A., Perkin, H., Hermanson, G., Anderson, C.G., Jolly, D.J., Maki, R.A. & Torbett, B.E. (1999). Blood, 94, 2310–18.PubMedGoogle Scholar
  4. Arinobu, Y., Iwasaki, H., Gurish, M.F., Mizuno, S., Shigematsu, H., Ozawa, H., Tenen, D.G., Austen, K.F. & Akashi, K. (2005). Proc Natl Acad Sci USA, 102, 18105–10.PubMedGoogle Scholar
  5. Arock, M., Schneider, E., Boissan, M., Tricottet, V. & Dy, M. (2002). J Leukoc Biol, 71, 557–64.PubMedGoogle Scholar
  6. Austen, K.F. & Boyce, J.A. (2001). Leuk Res, 25, 511–18.PubMedGoogle Scholar
  7. Baehner, R.L. (2000). Hematology: Basic Principles and Practice. Hoffman, R., Benz, E.J, Jr., Shattil, S.J., Furie, B., Cohen, H.J., Silberstein, L.E. & McGlave, P. (eds). Churchhill Livinstone: Philadelphia, PA, pp 667–686.Google Scholar
  8. Baker, S.J., Rane, S.G. & Reddy, E.P. (2007). Oncogene, 26, 6724–37.PubMedGoogle Scholar
  9. Bartel, D.P. (2004). Cell, 116, 281–97.PubMedGoogle Scholar
  10. Begg, S.K., Radley, J.M., Pollard, J.W., Chisholm, O.T., Stanley, E.R. & Bertoncello, I. (1993). J Exp Med, 177, 237–42.PubMedGoogle Scholar
  11. Brass, A.L., Zhu, A.Q. & Singh, H. (1999). EMBO J, 18, 977–91.PubMedGoogle Scholar
  12. Breton-Gorius, J., Mason, D.Y., Buriot, D., Vilde, J.L. & Griscelli, C. (1980). Am J Pathol, 99, 413–28.PubMedGoogle Scholar
  13. Cai, D.H., Wang, D., Keefer, J., Yeamans, C., Hensley, K. & Friedman, A.D. (2007). Oncogene, 27, 2772–9.PubMedGoogle Scholar
  14. Cammenga, J., Mulloy, J.C., Berguido, F.J., MacGrogan, D., Viale, A. & Nimer, S.D. (2003). Blood, 101, 2206–14.PubMedGoogle Scholar
  15. Cantor, A.B. & Orkin, S.H. (2001). Curr Opin Genet Dev, 11, 513–19.PubMedGoogle Scholar
  16. Cantor, A.B., Iwaski, H., Arinobu, Y., Moran, T.B., Shigematsu, H., Sullivan, M.R., Akashi, K. & Orkin, S.H. (2008). J Exp Med, 205, 611–24.PubMedGoogle Scholar
  17. Chen, C.Z., Li, L., Lodish, H.F. & Bartel, D.P. (2004). Science, 303, 83–6.PubMedGoogle Scholar
  18. Chitu, V. & Stanley, E.R. (2006). Curr Opin Immunol, 18, 39–48.PubMedGoogle Scholar
  19. Dahl, R., Walsh, J.C., Lancki, D., Laslo, P., Iyer, S.R., Singh, H. & Simon, M.C. (2003). Nat Immunol, 4, 1029–36.PubMedGoogle Scholar
  20. Dahl, R., Iyer, S.R., Owens, K.S., Cuylear, D.D. & Simon, M.C. (2006). J Biol Chem, 282, 6473–83.PubMedGoogle Scholar
  21. Dai, X.M., Ryan, G.R., Hapel, A.J., Dominguez, M.G., Russell, R.G., Kapp, S., Sylvestre, V. & Stanley, E.R. (2002). Blood, 99, 111–20.PubMedGoogle Scholar
  22. Dakic, A., Metcalf, D., Di Rago, L., Mifsud, S., Wu, L. & Nutt, S.L. (2005). J Exp Med, 201, 1487–502.PubMedGoogle Scholar
  23. Dalrymple, S.A., Lucian, L.A., Slattery, R., McNeil, T., Aud, D.M., Fuchino, S., Lee, F. & Murray, R. (1995). Infect Immun, 63, 2262–8.PubMedGoogle Scholar
  24. de The, H., Marchio, A., Tiollais, P. & Dejean, A. (1989). EMBO J, 8, 429–33.PubMedGoogle Scholar
  25. DeKoter, R.P. & Singh, H. (2000). Science, 288, 1439–41.PubMedGoogle Scholar
  26. DeKoter, R.P., Walsh, J.C. & Singh, H. (1998). EMBO J, 17, 4456–68.PubMedGoogle Scholar
  27. Eferl, R., Sibilia, M., Hilberg, F., Fuchsbichler, A., Kufferath, I., Guertl, B., Zenz, R., Wagner, E.F. & Zatloukal, K. (1999). J Cell Biol, 145, 1049–61.PubMedGoogle Scholar
  28. Eisenbeis, C.F., Singh, H. & Storb, U. (1995). Genes Dev, 9, 1377–87.PubMedGoogle Scholar
  29. Fairbairn, L.J., Cowling, G.J., Reipert, B.M. & Dexter, T.M. (1993). Cell, 74, 823–32.PubMedGoogle Scholar
  30. Faller, D.V. & Mentzer, S.J. (2000). Hematology: Basic Principles and Practice. Hoffman, R., Benz, E.J., Jr., Shattil, S.J., Furie, B., Cohen, H.J., Silberstein, L.E. & McGlave, P. (eds). Churchill Livinstone: Philadelphia, PA, pp 686–701.Google Scholar
  31. Fazi, F., Rosa, A., Fatica, A., Gelmetti, V., De Marchis, M.L., Nervi, C. & Bozzoni, I. (2005). Cell 123, 819–31.PubMedGoogle Scholar
  32. Feinberg, M.W., Wara, A.K., Cao, Z., Lebedeva, M.A., Rosenbauer, F., Iwasaki, H., Hirai, H., Katz, J.P., Haspel, R.L., Gray, S., Akashi, K., Segre, J., Kaestner, K.H., Tenen, D.G. & Jain, M.K. (2007). EMBO J, 26, 4138–48.PubMedGoogle Scholar
  33. Fontana, L., Pelosi, E., Greco, P., Racanicchi, S., Testa, U., Liuzzi, F., Croce, C.M., Brunetti, E., Grignani, F. & Peschle, C. (2007). Nat Cell Biol, 9, 775–87.PubMedGoogle Scholar
  34. Foster, P.S., Hogan, S.P., Ramsay, A.J., Matthaei, K.I. & Young, I.G. (1996). J Exp Med, 183, 195–201.PubMedGoogle Scholar
  35. Galli, S.J., Tsai, M. & Wershil, B.K. (1993). Am J Pathol, 142, 965–74.PubMedGoogle Scholar
  36. Gillessen, S., Mach, N., Small, C., Mihm, M. & Dranoff, G. (2001). Blood, 97, 922–8.PubMedGoogle Scholar
  37. Gleich, G.J., Ottesen, E.A., Leiferman, K.M. & Ackerman, S.J. (1989). Int Arch Allergy Appl Immunol, 88, 59–62.PubMedGoogle Scholar
  38. Gombart, A.F. & Koeffler, H.P. (2002). Curr Opin Hematol, 9, 36–42.PubMedGoogle Scholar
  39. Gombart, A.F., Shiohara, M., Kwok, S.H., Agematsu, K., Komiyama, A. & Koeffler, H.P. (2001). Blood, 97, 2561–7.PubMedGoogle Scholar
  40. Gorman, D.M., Itoh, N., Jenkins, N.A., Gilbert, D.J., Copeland, N.G. & Miyajima, A. (1992). J Biol Chem, 267, 15842–8.PubMedGoogle Scholar
  41. Harigae, H., Takahashi, S., Suwabe, N., Ohtsu, H., Gu, L., Yang, Z., Tsai, F.Y., Kitamura, Y., Engel, J.D. & Yamamoto, M. (1998). Genes Cells, 3, 39–50.PubMedGoogle Scholar
  42. Hass, R., Brach, M., Kharbanda, S., Giese, G., Traub, P. & Kufe, D. (1991). J Cell Physiol, 149, 125–31.PubMedGoogle Scholar
  43. Heath, V., Suh, H.C., Holman, M., Renn, K., Gooya, J.M., Parkin, S., Klarmann, K.D., Ortiz, M., Johnson, P. & Keller, J. (2004). Blood, 104, 1639–47.PubMedGoogle Scholar
  44. Hibbs, M.L., Quilici, C., Kountouri, N., Seymour, J.F., Armes, J.E., Burgess, A.W. & Dunn, A.R. (2007). J Immunol, 178, 6435–43.PubMedGoogle Scholar
  45. Hirasawa, R., Shimizu, R., Takahashi, S., Osawa, M., Takayanagi, S., Kato, Y., Onodera, M., Minegishi, N., Yamamoto, M., Fukao, K., Taniguchi, H., Nakauchi, H. & Iwama, A. (2002). J Exp Med, 195, 1379–86.PubMedGoogle Scholar
  46. Hisakawa, H., Sugiyama, D., Nishijima, I., Xu, M.J., Wu, H., Nakao, K., Watanabe, S., Katsuki, M., Asano, S., Arai, K., Nakahata, T. & Tsuji, K. (2001). Blood, 98, 3618–25.PubMedGoogle Scholar
  47. Hock, H., Hamblen, M.J., Rooke, H.M., Traver, D., Bronson, R.T., Cameron, S. & Orkin, S.H. (2003). Immunity, 18, 109–20.PubMedGoogle Scholar
  48. Hromas, R., Orazi, A., Neiman, R.S., Maki, R., Van Beveran, C., Moore, J. & Klemsz, M. (1993). Blood, 82, 2998–3004.PubMedGoogle Scholar
  49. Ichihara, M., Hara, T., Takagi, M., Cho, L.C., Gorman, D.M. & Miyajima, A. (1995). EMBO J, 14, 939–50.PubMedGoogle Scholar
  50. Iwama, A., Osawa, M., Hirasawa, R., Uchiyama, N., Kaneko, S., Onodera, M., Shibuya, K., Shibuya, A., Vinson, C., Tenen, D.G. & Nakauchi, H. (2002). J Exp Med, 195, 547–58.PubMedGoogle Scholar
  51. Iwasaki, H., Somoza, C., Shigematsu, H., Duprez, E.A., Iwasaki-Arai, J., Mizuno, S., Arinobu, Y., Geary, K., Zhang, P., Dayaram, T., Fenyus, M.L., Elf, S., Chan, S., Kastner, P., Huettner, C.S., Murray, R., Tenen, D.G. & Akashi, K. (2005). Blood, 106, 1590–600.PubMedGoogle Scholar
  52. Iwasaki, H., Mizuno, S., Arinobu, Y., Ozawa, H., Mori, Y., Shigematsu, H., Takatsu, K., Tenen, D.G. & Akashi, K. (2006). Genes Dev, 20, 3010–21.PubMedGoogle Scholar
  53. Iwasaki-Arai, J., Iwasaki, H., Miyamoto, T., Watanabe, S. & Akashi, K. (2003). J Exp Med, 197, 1311–22.PubMedGoogle Scholar
  54. Karsunky, H., Zeng, H., Schmidt, T., Zevnik, B., Kluge, R., Schmid, K.W., Duhrsen, U. & Moroy, T. (2002). Nat Genet, 30, 295–300.PubMedGoogle Scholar
  55. Khanna-Gupta, A., Sun, H., Zibello, T., Lee, H.M., Dahl, R., Boxer, L.A. & Berliner, N. (2007). Blood, 109, 4181–90.PubMedGoogle Scholar
  56. King, A.G., Kondo, M., Scherer, D.C. & Weissman, I.L. (2002). Proc Natl Acad Sci USA, 99, 4508–13.PubMedGoogle Scholar
  57. Koike, M., Chumakov, A.M., Takeuchi, S., Tasaka, T., Yang, R., Nakamaki, T., Tsuruoka, N. & Koeffler, H.P. (1997). Leuk Res, 21, 833–9.PubMedGoogle Scholar
  58. Kondo, M., Scherer, D.C., Miyamoto, T., King, A.G., Akashi, K., Sugamura, K. & Weissman, I.L. (2000). Nature, 407, 383–6.PubMedGoogle Scholar
  59. Kopf, M., Brombacher, F., Hodgkin, P.D., Ramsay, A.J., Milbourne, E.A., Dai, W.J., Ovington, K.S., Behm, C.A., Kohler, G., Young, I.G. & Matthaei, K.I. (1996). Immunity, 4, 15–24.PubMedGoogle Scholar
  60. Krishnaraju, K., Hoffman, B. & Liebermann, D.A. (2001). Blood, 97, 1298–305.PubMedGoogle Scholar
  61. Krysinska, H., Hoogenkamp, M., Ingram, R., Wilson, N., Tagoh, H., Laslo, P., Singh, H. & Bonifer, C. (2006). Mol Cell Biol, 27, 878–87.PubMedGoogle Scholar
  62. Kulessa, H., Frampton, J. & Graf, T. (1995). Genes Dev, 9, 1250–62.PubMedGoogle Scholar
  63. Labrecque, J., Allan, D., Chambon, P., Iscove, N.N., Lohnes, D. & Hoang, T. (1998). Blood, 92, 607–15.PubMedGoogle Scholar
  64. Lagasse, E. & Weissman, I.L. (1997). Cell, 89, 1021–31.PubMedGoogle Scholar
  65. Laiosa, C.V., Stadtfeld, M., Xie, H., de Andres-Aguayo, L. & Graf, T. (2006). Immunity, 25, 731–44.PubMedGoogle Scholar
  66. Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., Pfeffer, S., Rice, A., Kamphorst, A.O., Landthaler, M., Lin, C., Socci, N.D., Hermida, L., Fulci, V., Chiaretti, S., Foa, R., Schliwka, J., Fuchs, U., Novosel, A., Muller, R.U., Schermer, B., Bissels, U., Inman, J., Phan, Q., Chien, M., Weir, D.B., Choksi, R., De Vita, G., Frezzetti, D., Trompeter, H.I., Hornung, V., Teng, G., Hartmann, G., Palkovits, M., Di Lauro, R., Wernet, P., Macino, G., Rogler, C.E., Nagle, J.W., Ju, J., Papavasiliou, F.N., Benzing, T., Lichter P T a m W Brownstein, M.J., Bosio, A., Borkhardt, A., Russo, J.J., Sander, C., Zavolan, M. & Tuschl, T. (2007). Cell, 129, 1401–14.PubMedGoogle Scholar
  67. Lantz, C.S. & Huff, T.F. (1995). J Immunol, 155, 4024–9.PubMedGoogle Scholar
  68. Lantz, C.S., Boesiger, J., Song, C.H., Mach, N., Kobayashi, T., Mulligan, R.C., Nawa, Y., Dranoff, G. & Galli, S.J. (1998). Nature, 392, 90–3.PubMedGoogle Scholar
  69. Laslo, P., Spooner, C.J., Warmflash, A., Lancki, D.W., Lee, H.J., Sciammas, R., Gantner, B.N., Dinner, A.R. & Singh, H. (2006). Cell, 126, 755–66.PubMedGoogle Scholar
  70. Lee, J.S. & Young, I.G. (1989). Genomics, 5, 359–62.PubMedGoogle Scholar
  71. Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J., Lee, J., Provost, P., Radmark, O., Kim, S. & Kim, V.N. (2003). Nature, 425, 415–19.PubMedGoogle Scholar
  72. Lee, Y., Kim, M., Han, J., Yeom, K.H., Lee, S., Baek, S.H. & Kim, V.N. (2004a). EMBO J, 23, 4051–60.Google Scholar
  73. Lee, Y.S., Nakahara, K., Pham, J.W., Kim, K., He, Z., Sontheimer, E.J. & Carthew, R.W. (2004b). Cell, 117, 69–81.Google Scholar
  74. Lekstrom-Himes, J. & Xanthopoulos, K.G. (1999). Blood, 93, 3096–105.PubMedGoogle Scholar
  75. Lekstrom-Himes, J.A., Dorman, S.E., Kopar, P., Holland, S.M. & Gallin, J.I. (1999). J Exp Med, 189, 1847–52.PubMedGoogle Scholar
  76. Lieschke, G.J. (1997). Ciba Found Symp, 204, 60–74; discussion 74–7.Google Scholar
  77. Lieschke, G.J., Grail, D., Hodgson, G., Metcalf, D., Stanley, E., Cheers, C., Fowler, K.J., Basu, S., Zhan, Y.F. & Dunn, A.R. (1994a). Blood, 84, 1737–46.Google Scholar
  78. Lieschke, G.J., Stanley, E., Grail, D., Hodgson, G., Sinickas, V., Gall, J.A., Sinclair, R.A. & Dunn, A.R. (1994b). Blood, 84, 27–35.Google Scholar
  79. Liu, F., Wu, H.Y., Wesselschmidt, R., Kornaga, T. & Link, D.C. (1996). Immunity, 5, 491–501.PubMedGoogle Scholar
  80. Liu, F., Poursine-Laurent, J., Wu, H.Y. & Link, D.C. (1997). Blood, 90, 2583–90.PubMedGoogle Scholar
  81. Mach, N., Lantz, C.S., Galli, S.J., Reznikoff, G., Mihm, M., Small, C., Granstein, R., Beissert, S., Sadelain, M., Mulligan, R.C. & Dranoff, G. (1998). Blood, 91, 778–83.PubMedGoogle Scholar
  82. McKercher, S.R., Torbett, B.E., Anderson, K.L., Henkel, G.W., Vestal, D.J., Baribault, H., Klemsz, M., Feeney, A.J., Wu, G.E., Paige, C.J. & Maki, R.A. (1996). EMBO J, 15, 5647–58.PubMedGoogle Scholar
  83. Nagata, H., Worobec, A.S., Oh, C.K., Chowdhury, B.A., Tannenbaum, S., Suzuki, Y. & Metcalfe, D.D. (1995). Proc Natl Acad Sci USA, 92, 10560–4.PubMedGoogle Scholar
  84. Nerlov, C., McNagny, K.M., Doderlein, G., Kowenz-Leutz, E. & Graf, T. (1998). Genes Dev, 12, 2413–23.PubMedGoogle Scholar
  85. Nicola, N.A., Robb, L., Metcalf, D., Cary, D., Drinkwater, C.C. & Begley, C.G. (1996). Blood, 87, 2665–74.PubMedGoogle Scholar
  86. Nilsson, S.K. & Bertoncello, I. (1994). Dev Biol, 164, 456–62.PubMedGoogle Scholar
  87. Nishinakamura, R., Miyajima, A., Mee, P.J., Tybulewicz, V.L. & Murray, R. (1996). Blood, 88, 2458–64.PubMedGoogle Scholar
  88. Owen, W.F., Jr., Rothenberg, M.E., Silberstein, D.S., Gasson, J.C., Stevens, R.L., Austen, K.F. & Soberman, R.J. (1987). J Exp Med, 166, 129–41.PubMedGoogle Scholar
  89. Passegue, E., Jochum, W., Schorpp-Kistner, M., Mohle-Steinlein, U. & Wagner, E.F. (2001). Cell 104, 21–32.PubMedGoogle Scholar
  90. Passegue, E., Wagner, E.F. & Weissman, I.L. (2004). Cell, 119, 431–43.PubMedGoogle Scholar
  91. Person, R.E., Li, F.Q., Duan, Z., Benson, K.F., Wechsler, J., Papadaki, H.A., Eliopoulos, G., Kaufman, C., Bertolone, S.J., Nakamoto, B., Papayannopoulou, T., Grimes, H.L. & Horwitz, M. (2003). Nat Genet, 34, 308–12.PubMedGoogle Scholar
  92. Pevny, L., Simon, M.C., Robertson, E., Klein, W.H., Tsai, S.F., D'Agati, V., Orkin, S.H. & Costantini, F. (1991). Nature, 349, 257–60.PubMedGoogle Scholar
  93. Pojda, Z. & Tsuboi, A. (1990). Exp Hematol, 18, 1034–7.PubMedGoogle Scholar
  94. Querfurth, E., Schuster, M., Kulessa, H., Crispino, J.D., Doderlein, G., Orkin, S.H., Graf, T. & Nerlov, C. (2000). Genes Dev, 14, 2515–25.PubMedGoogle Scholar
  95. Radomska, H.S., Huettner, C.S., Zhang, P., Cheng, T., Scadden, D.T. & Tenen, D.G. (1998). Mol Cell Biol, 18, 4301–14.PubMedGoogle Scholar
  96. Rane, S.G. & Reddy, E.P. (2002). Oncogene, 21, 3334–58.PubMedGoogle Scholar
  97. Reddy, E.P., Korapati, A., Chaturvedi, P. & Rane, S. (2000). Oncogene, 19, 2532–47.PubMedGoogle Scholar
  98. Reddy, V.A., Iwama, A., Iotzova, G., Schulz, M., Elsasser, A., Vangala, R.K., Tenen, D.G., Hiddemann, W. & Behre, G. (2002). Blood, 100, 483–90.PubMedGoogle Scholar
  99. Rekhtman, N., Radparvar, F., Evans, T. & Skoultchi, A.I. (1999). Genes Dev, 13, 1398–411.PubMedGoogle Scholar
  100. Rhodes, J., Hagen, A., Hsu, K., Deng, M., Liu, T.X., Look, A.T. & Kanki, J.P. (2005). Dev Cell 8, 97–108.PubMedGoogle Scholar
  101. Richards, M.K., Liu, F., Iwasaki, H., Akashi, K. & Link, D.C. (2003). Blood, 102, 3562–8.PubMedGoogle Scholar
  102. Rodriguez, A., Vigorito, E., Clare, S., Warren, M.V., Couttet, P., Soond, D.R., van Dongen, S., Grocock, R.J., Das, P.P., Miska, E.A., Vetrie, D., Okkenhaug, K., Enright, A.J., Dougan, G., Turner, M. & Bradley, A. (2007). Science, 316, 608–11.PubMedGoogle Scholar
  103. Romani, L., Mencacci, A., Cenci, E., Spaccapelo, R., Toniatti, C., Puccetti, P., Bistoni, F. & Poli, V. (1996). J Exp Med, 183, 1345–55.PubMedGoogle Scholar
  104. Scott, E.W., Simon, M.C., Anastasi, J. & Singh, H. (1994). Science, 265, 1573–7.PubMedGoogle Scholar
  105. Scott, L.M., Civin, C.I., Rorth, P. & Friedman, A.D. (1992). Blood, 80, 1725–35.PubMedGoogle Scholar
  106. Seymour, J.F., Lieschke, G.J., Grail, D., Quilici, C., Hodgson, G. & Dunn, A.R. (1997). Blood, 90, 3037–49.PubMedGoogle Scholar
  107. Sherman, M.L., Stone, R.M., Datta, R., Bernstein, S.H. & Kufe, D.W. (1990). J Biol Chem, 265, 3320–3.PubMedGoogle Scholar
  108. Shibata, Y., Berclaz, P.Y., Chroneos, Z.C., Yoshida, M., Whitsett, J.A. & Trapnell, B.C. (2001). Immunity, 15, 557–67.PubMedGoogle Scholar
  109. Shivdasani, R.A., Fujiwara, Y., McDevitt, M.A. & Orkin, S.H. (1997). EMBO J, 16, 3965–73.PubMedGoogle Scholar
  110. Skokowa, J., Cario, G., Uenalan, M., Schambach, A., Germeshausen, M., Battmer, K., Zeidler, C., Lehmann, U., Eder, M., Baum, C., Grosschedl, R., Stanulla, M., Scherr, M. & Welte, K. (2006). Nat Med, 12, 1191–7.PubMedGoogle Scholar
  111. Stanley, E.R. (1985). Methods Enzymol, 116, 564–87.PubMedGoogle Scholar
  112. Stanley, E.R., Guilbert, L.J., Tushinski, R.J. & Bartelmez, S.H. (1983). J Cell Biochem, 21, 151–9.PubMedGoogle Scholar
  113. Stopka, T., Amanatullah, D.F., Papetti, M. & Skoultchi, A.I. (2005). EMBO J, 24, 3712–23.PubMedGoogle Scholar
  114. Sugiyama, D., Tanaka, M., Kitajima, K., Zheng, J., Yen, H., Murotani, T., Yamatodani, A. & Nakano, T. (2008). Blood, 111, 1924–32.PubMedGoogle Scholar
  115. Suh, H.C., Gooya, J., Renn, K., Friedman, A.D., Johnson, P.F. & Keller, J.R. (2006). Blood, 107, 4308–16.PubMedGoogle Scholar
  116. Tamura, T., Nagamura-Inoue, T., Shmeltzer, Z., Kuwata, T. & Ozato, K. (2000). Immunity, 13, 155–65.PubMedGoogle Scholar
  117. Tanno, Y., Stadler, B. & Denburg, J.A. (1987). Int Arch Allergy Appl Immunol, 83, 1–5.PubMedGoogle Scholar
  118. Thai, T.H., Calado, D.P., Casola, S., Ansel, K.M., Xiao, C., Xue, Y., Murphy, A., Frendewey, D., Valenzuela, D., Kutok, J.L., Schmidt-Supprian, M., Rajewsky, N., Yancopoulos, G., Rao, A. & Rajewsky, K. (2007). Science, 316, 604–8.PubMedGoogle Scholar
  119. Tsai, F.Y. & Orkin, S.H. (1997). Blood, 89, 3636–43.PubMedGoogle Scholar
  120. Tsai, S. & Collins, S.J. (1993). Proc Natl Acad Sci USA, 90, 7153–7.PubMedGoogle Scholar
  121. Tsang, A.P., Visvader, J.E., Turner, C.A., Fujiwara, Y., Yu, C., Weiss, M.J., Crossley, M. & Orkin, S.H. (1997). Cell, 90, 109–19.PubMedGoogle Scholar
  122. Walsh, J.C., DeKoter, R.P., Lee, H.J., Smith, E.D., Lancki, D.W., Gurish, M.F., Friend, D.S., Stevens, R.L., Anastasi, J. & Singh, H. (2002). Immunity, 17, 665–76.PubMedGoogle Scholar
  123. Wang, D., D'Costa, J., Civin, C.I. & Friedman, A.D. (2006). Blood, 108, 1223–9.PubMedGoogle Scholar
  124. Welch, J.J., Watts, J.A., Vakoc, C.R., Yao, Y., Wang, H., Hardison, R.C., Blobel, G.A., Chodosh, L.A. & Weiss, M.J. (2004). Blood, 104, 3136–47.PubMedGoogle Scholar
  125. Wiktor-Jedrzejczak, W., Bartocci, A., Ferrante, A.W.Jr., Ahmed-Ansari, A., Sell, K.W., Pollard, J.W. & Stanley, E.R. (1990). Proc Natl Acad Sci USA, 87, 4828–32.Google Scholar
  126. Xiao, C., Calado, D.P., Galler, G., Thai, T.H., Patterson, H.C., Wang, J., Rajewsky, N., Bender, T.P. & Rajewsky, K. (2007). Cell, 131, 146–59.PubMedGoogle Scholar
  127. Xie, H., Ye, M., Feng, R. & Graf, T. (2004). Cell, 117, 663–76.PubMedGoogle Scholar
  128. Yamaguchi, Y., Suda, T., Suda, J., Eguchi, M., Miura, Y., Harada, N., Tominaga, A. & Takatsu, K. (1988). J Exp Med, 167, 43–56.PubMedGoogle Scholar
  129. Yamanaka, R., Kim, G.D., Radomska, H.S., Lekstrom-Himes, J., Smith, L.T., Antonson, P., Tenen, D.G. & Xanthopoulos, K.G. (1997). Proc Natl Acad Sci USA, 94, 6462–7.PubMedGoogle Scholar
  130. Yoshida, H., Hayashi, S., Kunisada, T., Ogawa, M., Nishikawa, S., Okamura, H., Sudo, T. & Shultz, L.D. (1990). Nature, 345, 442–4.PubMedGoogle Scholar
  131. Yu, C., Cantor, A.B., Yang, H., Browne, C., Wells, R.A., Fujiwara, Y. & Orkin, S.H. (2002). J Exp Med, 195, 1387–95.PubMedGoogle Scholar
  132. Yuan, W., Payton, J.E., Holt, M.S., Link, D.C., Watson, M.A., DiPersio, J.F. & Ley, T.J. (2007). Blood, 109, 961–70.PubMedGoogle Scholar
  133. Zhang, D.E., Zhang, P., Wang, N.D., Hetherington, C.J., Darlington, G.J. & Tenen, D.G. (1997). Proc Natl Acad Sci USA, 94, 569–74.PubMedGoogle Scholar
  134. Zhang, P., Iwasaki-Arai, J., Iwasaki, H., Fenyus, M.L., Dayaram, T., Owens, B.M., Shigematsu, H., Levantini, E., Huettner, C.S., Lekstrom-Himes, J.A., Akashi, K. & Tenen, D.G. (2004). Immunity, 21, 853–63.PubMedGoogle Scholar
  135. Zon, L.I., Yamaguchi, Y., Yee, K., Albee, E.A., Kimura, A., Bennett, J.C., Orkin, S.H. & Ackerman, S.J. (1993). Blood, 81, 3234–41.PubMedGoogle Scholar

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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.University of New Mexico Health Sciences CenterAlbuquerqueUSA

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