Bioinformatics Analysis: Gene Fusion
Gene fusion is an important evolutionary phenomenon. Human fusion proteins consisting of two or more fusion partners of bacterial origin exhibit accreted (enhanced or novel) function. These proteins mimic operons, simulate protein subunit interfaces in bacteria, exhibit multiple functions, and show alternative splicing in humans. They are also associated with metabolites having greater connectivity in complex networks.
KeywordsFusion Protein Lateral Gene Transfer Fusion Event Fusion Partner Mycobacterium Smegmatis
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