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Bioinformatics Application: Eukaryotic Gene Count and Evolution

  • Meena K. Sakharkar
  • Pandjassarame Kangueane

Abstract

In this chapter, we describe the comparison of gene numbers in different eukaryotic genomes. Unlike prokaryotes, eukaryotic genes are often split into exons (coding sequence segments) and introns (non-coding sequence segments). However, the number of exons and introns vary in different genes across diverse genome species. It is found that the intron number varies from 0 to $>$100 in different eukaryotic genes. This results in SEG (Single exon genes) and MEG (multi exon genes). Thus, SEG have 0 intron and MEG have at least one intron. Consequently, we compared the SEG and MEG fraction across different eukaryotic genomes. The comparison helped to discuss the evolutionary selection of SEG and MEG fraction in eukaryotic genomes.

Keywords

Genome Size Eukaryotic Genome Gene Density Genome SEGE Gene Count 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Meena K. Sakharkar
    • 1
  • Pandjassarame Kangueane
    • 2
  1. 1.Nanyang Technological UniversitySingapore
  2. 2.Biomedical InformaticsIndia

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