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Cadmium-induced renal effects

  • Gunnar F. Nordberg
  • Teruhiko Kido
  • Harry A. Roels

The first observations on adverse renal effects of cadmium (Cd) exposure in humans were made by Friberg in the late 1940s [1]. He reported a high prevalence of proteinuria (65% using the nitric acid test and 81% using the trichloroacetic acid test) in Cd-exposed workers.

In Japan, an unusual disease named “itai-itai byo” or “ouch-ouch disease” was reported in 1955 [2]. This disease is characterized clinically by bone and kidney damage. In 1968, the Japanese Ministry of Health and Welfare concluded that itai-itai disease was caused by chronic Cd poisoning [3].

Keywords

Cadmium Exposure Renal Tubular Dysfunction Arch Environ Health Jinzu River Basin Kakehashi River Basin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Gunnar F. Nordberg
    • 1
  • Teruhiko Kido
    • 2
  • Harry A. Roels
    • 3
  1. 1.Environmental Medicine Department of Public Health and Clinical MedicineUmea UniversityUmeaSweden
  2. 2.Faculty of Medicine School of Health SciencesKanazawa UniversityKanazawaJapan
  3. 3.Industrial Toxicology and Occupational Medicine UnitUniversité catholique de LouvainBrusselsBelgium

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