Current Concepts of Orthopedic Implants and Prosthetic Joint Infections

Part of the Emerging Infectious Diseases of the 21st Century book series (EIDC)

It is estimated that approximately two million fracture-fixation devices (intrame-dultory nails, external-fixation pins, plates, and screws) and about 600,000 joint prosthesis are inserted annually in the United States.1 Projected infections of joint prosthesis (average rate of 2%) is 12,000 and fracture-fixation devices (average 5%) is 1,000,000 annually. Infections of these orthopedic devices causes substantial morbidity and health care expenditure, with an estimated average cost for combined medical and surgical treatment of US$30,000 for an infected prosthesis, and US $15,000 for an infected fracture-fixation device.1 Hence a conservative estimate of US$1.8 billion is spent annually for the management of infected orthopedic implants in the United States.

Although progress has been made in the last decade on the pathogenesis of this biofilm infection, there is still considerable debate and lack of standardization on the diagnosis, methods to establish the bacteriology and management. Despite the enormity of the problems posed by these orthopedic implant infections in developed countries, there is a lack of proper controlled, randomized trials on medical and surgical therapy.


Surgical Site Infection Prosthetic Joint Infection Orthopedic Implant Periprosthetic Tissue Infected Total Knee Arthroplasties 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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