Malignant adnexal neoplasms are rare tumors derived from apocrine, eccrine, sebaceous and follicular adnexal structures. Herein, the malignant tumors of eccrine differentiation will be reviewed. The histological features that distinguish these neoplasms from each other and from benign tumors, as well as the features that are found when these tumors locally invade neighboring tissue and/or metastasize, are discussed.
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